Library / English Dictionary

    RAF

    Pronunciation (US): Play  (GB): Play

     I. (noun) 

    Sense 1

    Meaning:

    A Marxist and Maoist terrorist organization in Germany; a network of underground guerillas who committed acts of violence in the service of the class struggle; a successor to the Baader-Meinhof Gang; became one of Europe's most feared terrorist groups; disbanded in 1998play

    Synonyms:

    RAF; Red Army Faction

    Classified under:

    Nouns denoting groupings of people or objects

    Instance hypernyms:

    foreign terrorist organization; FTO; terrorist group; terrorist organization (a political movement that uses terror as a weapon to achieve its goals)

    Domain category:

    act of terrorism; terrorism; terrorist act (the calculated use of violence (or the threat of violence) against civilians in order to attain goals that are political or religious or ideological in nature; this is done through intimidation or coercion or instilling fear)

    Domain region:

    Deutschland; Federal Republic of Germany; FRG; Germany (a republic in central Europe; split into East Germany and West Germany after World War II and reunited in 1990)

    Sense 2

    Meaning:

    The airforce of Great Britainplay

    Synonyms:

    RAF; Royal Air Force

    Classified under:

    Nouns denoting groupings of people or objects

    Hypernyms ("RAF" is a kind of...):

    air force; airforce (the airborne branch of a country's armed forces)

    Credits

     Context examples: 

    CEP-32496 specifically and selectively inhibits the activity of the mutated form (V600E) of B-raf kinase.

    (BRAF(V600E) Inhibitor CEP-32496, NCI Thesaurus)

    An orally bioavailable, highly soluble phosphate prodrug of B-raf (BRAF) protein kinase with potential antineoplastic activity.

    (BRAF Inhibitor ARQ 736, NCI Thesaurus)

    A variation in the amino acid sequence for the serine/threonine-protein kinase B-raf protein.

    (BRAF Protein Variant, NCI Thesaurus)

    An orally bioavailable inhibitor of serine/threonine-protein kinase B-raf (BRAF) protein with potential antineoplastic activity.

    (BRAF Inhibitor PLX8394, NCI Thesaurus)

    A gene that makes a protein called B-RAF, which is involved in sending signals in cells and in cell growth.

    (BRAF gene, NCI Dictionary)

    A change in the valine at position 600 of the serine/threonine-protein kinase B-raf protein to another amino acid.

    (BRAF V600 Protein Variation, NCI Thesaurus)

    MEK1/2 are dual-specificity threonine/tyrosine kinases that play key roles in the activation of the RAS/RAF/MEK/ERK pathway and are often upregulated in a variety of tumor cell types.

    (MEK Inhibitor MEK162, NCI Thesaurus)

    The dual specific threonine/tyrosine kinase MEK is a key component of the RAS/RAF/MEK/ERK signaling pathway that is frequently activated in human tumors.

    (PD0325901, NCI Thesaurus)

    MEK is a key component of the RAS/RAF/MEK/ERK signaling pathway that regulates cell growth; constitutive activation of this pathway has been implicated in many cancers.

    (MEK Inhibitor AZD8330, NCI Thesaurus)

    MEK, a dual-specificity threonine/tyrosine kinase that plays a key role in the activation of the RAS/RAF/MEK/ERK signaling pathway, is frequently upregulated in a variety of tumor cell types.

    (MEK Inhibitor WX-554, NCI Thesaurus)


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