Health / Medical Topics

    RARA/PML Fusion Gene

    A fusion gene that results from a chromosomal translocation t(15;17)(q22;q21) which fuses the first 2 exons of the RARA gene with the last six exons of the PML gene. A transcript of this gene fusion is associated with acute promyelocytic leukemia. (NCI Thesaurus)




    YOU MAY ALSO LIKE

    Human RARA wild-type allele is located within 17q21 and is approximately 48 kb in length. This allele, which encodes retinoic acid receptor…
    This gene plays a role in transcription and retinoic acid receptor signal transduction.
    Once retinoids are bound by the RAR/RXR heterodimer they became transcriptional activated. As a consequence they are degraded by the proteasome. Phosphorylation…
    A monoclonal antibody used to treat psoriasis (a chronic skin disease). It is also being studied in the treatment of graft-versus-host disease…
    Acting or occurring in a brief period of time.
    A substance that acts quickly to treat moderate to severe pain. Opioids are like opiates, such as morphine and codeine, but are…

    © 1991-2023 The Titi Tudorancea Bulletin | Titi Tudorancea® is a Registered Trademark | Terms of use and privacy policy
    Contact