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Receptor Binding
Receptor Binding involves a temporary non-covalent, typically highly specific and high affinity, interaction through intermolecular physical forces of attraction and spatial complementarity with a diverse group of intrinsic membrane or cytoplasmic proteins that mediate the biological effects of secreted regulatory signaling molecules through modification of the activity of signal transduction pathways. (NCI Thesaurus)
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Document type (funding opportunity): a PA or RFA not requiring clearance at the NCI Board of Scientific Advisors
