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RECOMBINANT
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A cell or organism in which genetic recombination has occurred
Classified under:
Hypernyms ("recombinant" is a kind of...):
being; organism (a living thing that has (or can develop) the ability to act or function independently)
cell ((biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals)
II. (adjective)
Sense 1
Meaning:
Of or relating to recombinant DNA
Classified under:
Relational adjectives (pertainyms)
Pertainym:
recombinant DNA (genetically engineered DNA made by recombining fragments of DNA from different organisms)
Context examples:
A replication-defective recombinant canarypox virus (ALVAC) that contains the entire human carcinoembryonic antigen (CEA) gene.
(ALVAC-CEA (VCP248), NCI Thesaurus)
A recombinant, murine monoclonal antibody directed against gastrin-releasing peptide, one of a number of bombesin-like peptides (BLP).
(Monoclonal Antibody 2A11, NCI Thesaurus)
A cancer vaccine consisting of a proprietary, recombinant modified vaccinia Ankara (MVA) viral vector encoding an epitope of human epidermal growth factor receptor 2 (HER2) with potential antineoplastic activity.
(Modified Vaccinia Ankara (Bavarian Nordic)-HER2 Vaccine, NCI Thesaurus)
A therapeutic cancer vaccine, based on a replication-defective recombinant canarypox virus (ALVAC) encoding multiple melanoma antigens, with potential immunostimulatory and antineoplastic activities.
(ALVAC(2) Melanoma Multi-antigen Vaccine, NCI Thesaurus)
The recombinant protein molecule SA-4-1BBL has been used to enhance the therapeutic efficacy of cancer vaccines with success in pre-clinical animal models.
(Immune Stimulant Molecule Protects against Cancer Development, The Titi Tudorancea Bulletin)
A recombinant monoclonal antibody in which the heavy and light chain variable domains mimic a specific epitope of the tumor-associated protein carcinoembryonic antigen (CEA).
(Monoclonal Antibody 3H1 Anti-Idiotype Vaccine, NCI Thesaurus)
A pegylated form of recombinant human erythropoietin, a glycosylated protein naturally produced in the kidney that stimulates erythrocyte production in the bone marrow.
(Methoxy Polyethylene Glycol-Epoetin beta, NCI Thesaurus)
A recombinant fusion protein derived from the coding sequences of two growth factors, interleukin-3 (IL-3) and granulocyte-macrophage colony-stimulating factor (GM-CSF).
(Milodistim, NCI Thesaurus)
Also called anti-IGF1R recombinant monoclonal antibody MK-0646.
(MK-0646, NCI Dictionary)
A recombinant immunoglobulin antibody directed against the tumor-associated carcinoembryonic antigen (CEA).
(Monoclonal Antibody COL-6, NCI Thesaurus)
