| Health / Medical Topics |
Recombinant Vaccinia-PSA(L155)-TRICOM Vaccine
A recombinant vaccinia virus encoding a modified peptide of the prostate-specific antigen (PSA) with a leucine substitution at position 155, and a TRIad of COstimulatory Molecules (B7-1, ICAM-1 and LFA-3). Vaccination with this viral vaccine may enhance antigen presentation and may activate cytotoxic T-cells against PSA-expressing tumor cells. (NCI Thesaurus)
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