Library / English Dictionary

    REDUCTASE

    Pronunciation (US): Play  (GB): Play

     I. (noun) 

    Sense 1

    Meaning:

    An enzyme that catalyses the biochemical reduction of some specified substanceplay

    Classified under:

    Nouns denoting substances

    Hypernyms ("reductase" is a kind of...):

    enzyme (any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions)

    Hyponyms (each of the following is a kind of "reductase"):

    5-hydroxy-3-methylglutaryl-coenzyme A reductase; HMG-CoA reductase (a liver enzyme that is responsible for producing cholesterol)

    Credits

     Context examples: 

    Interruption of the ICP6 gene, which encodes the large subunit of the viral ribonucleotide reductase, in the viral vector also enhances selective replication in tumor cells.

    (Oncolytic Herpes Simplex Virus-1-encoding GM-CSF, NCI Thesaurus)

    NADPH—cytochrome P450 reductase (677 aa, ~77 kDa) is encoded by the human POR gene.

    (NADPH--Cytochrome P450 Reductase, NCI Thesaurus)

    Auranofin interacts with selenocysteine residue within the redox-active domain of mitochondrial thioredoxin reductase (TrxR), thereby blocking the activity of TrxR.

    (Auranofin, NCI Thesaurus)

    Carbonyl reductase [NADPH] 3 (277 aa, ~31 kDa) is encoded by the human CBR3 gene.

    (Carbonyl Reductase [NADPH] 3, NCI Thesaurus)

    Aldo-keto reductase family 1 member C2 (323 aa, ~37 kDa) is encoded by the human AKR1C2 gene.

    (Aldo-Keto Reductase Family 1 Member C2, NCI Thesaurus)

    F-Ade inhibits DNA polymerase alpha, ribonucleotide reductase and DNA primase, thereby interrupting DNA synthesis and inhibiting tumor cell growth.

    (Adenovirus-Encoding E.coli PNP, NCI Thesaurus)

    Aldo-keto reductase family 1 member C1 (323 aa, ~37 kDa) is encoded by the human AKR1C1 gene.

    (Aldo-Keto Reductase Family 1 Member C1, NCI Thesaurus)

    This allele, which encodes aldo-keto reductase family 1 member C2 protein, is involved in the metabolism of steroid hormones and the inactivation of androgens.

    (AKR1C2 wt Allele, NCI Thesaurus)

    This species is acid fast, nonmotile, urease negative and catalase, nitrate reductase, and esculin positive.

    (Mycobacterium fortuitum, NCI Thesaurus)

    This allele, which encodes methionine synthase reductase protein, is involved in both B vitamin metabolism and methionine synthesis.

    (MTRR wt Allele, NCI Thesaurus)


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