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REGULATOR
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A control that maintains a steady speed in a machine (as by controlling the supply of fuel)
Synonyms:
Classified under:
Nouns denoting man-made objects
Hypernyms ("regulator" is a kind of...):
control; controller (a mechanism that controls the operation of a machine)
Hyponyms (each of the following is a kind of "regulator"):
flywheel (regulator consisting of a heavy wheel that stores kinetic energy and smooths the operation of a reciprocating engine)
timer (a regulator that activates or deactivates a mechanism at set times)
Sense 2
Meaning:
Any of various controls or devices for regulating or controlling fluid flow, pressure, temperature, etc.
Classified under:
Nouns denoting man-made objects
Hypernyms ("regulator" is a kind of...):
control; controller (a mechanism that controls the operation of a machine)
Hyponyms (each of the following is a kind of "regulator"):
aperture (a device that controls amount of light admitted)
ball cock; ballcock (floating ball that controls level in a water tank)
draft (a regulator for controlling the flow of air in a fireplace)
faucet; spigot (a regulator for controlling the flow of a liquid from a reservoir)
peg (regulator that can be turned to regulate the pitch of the strings of a stringed instrument)
petcock (regulator consisting of a small cock or faucet or valve for letting out air or releasing compression or draining)
register (a regulator (as a sliding plate) for regulating the flow of air into a furnace or other heating device)
escape; escape cock; escape valve; relief valve; safety valve (a valve in a container in which pressure can build up (as a steam boiler); it opens automatically when the pressure reaches a dangerous level)
floodgate; head gate; penstock; sluice valve; sluicegate; water gate (regulator consisting of a valve or gate that controls the rate of water flow through a sluice)
thermoregulator; thermostat (a regulator for automatically regulating temperature by starting or stopping the supply of heat)
Derivation:
regulate (fix or adjust the time, amount, degree, or rate of)
Sense 3
Meaning:
An official responsible for control and supervision of a particular activity or area of public interest
Classified under:
Hypernyms ("regulator" is a kind of...):
functionary; official (a worker who holds or is invested with an office)
Derivation:
regulate (bring into conformity with rules or principles or usage; impose regulations)
Context examples:
Nitrogen permease regulator 3-like protein (569 aa, ~64 kDa) is encoded by the human NPRL3 gene.
(Nitrogen Permease Regulator 3-Like Protein, NCI Thesaurus)
Once released, NICD moves into the nucleus where it is involved in transcriptional regulation through CSL family transcription factors (CBF1, Su(H), Lag-1) or other transcriptional regulators such as LEF-1.
(Notch and Wnt Signaling Pathway, NCI Thesaurus/BIOCARTA)
HDM2, a zinc finger protein and a negative regulator of the p53 pathway, is often overexpressed in cancer cells.
(p53-HDM2 Interaction Inhibitor MI-773, NCI Thesaurus)
HDM2, a zinc finger nuclear phosphoprotein, is a negative regulator of the p53 pathway, often overexpressed in cancer cells and has been implicated in cancer cell proliferation and survival.
(p53/HDM2 Interaction Inhibitor CGM097, NCI Thesaurus)
This allele, which encodes the PRKC apoptosis WT1 regulator protein, plays a role in both transcriptional repression and apoptosis activation.
(PAWR wt Allele, NCI Thesaurus)
PTEN, a tumor suppressor protein and negative regulator of PI3K activity, is often mutated in a variety of cancer cells.
(PI3K Alpha/Beta Inhibitor BAY1082439, NCI Thesaurus)
This agent also stimulates the T-cell-dependent development of IgG-secreting B-cells in spleen cell cultures and may be an important regulator of megakaryocytopoiesis.
(Oprelvekin, NCI Thesaurus)
Viral Oncogene E1B encodes 55-kDa E1B Protein, a regulator of early and late viral gene expression.
(Oncogene E1B, NCI Thesaurus)
This allele, which encodes nitrogen permease regulator 3-like protein, has no known function.
(NPRL3 wt Allele, NCI Thesaurus)
One of these proteins is a negative regulator of transcriptional activation by AP-2.
(Oncogene AP2, NCI Thesaurus)
