Health / Medical Topics

    Retinoic Acid Receptor

    Definition 1

    Retinoid receptors (RARA, RARB, RARG) require co-regulators to increase selective binding to DNA response elements in target genes and enhance transcriptional activity. (NCI Thesaurus)

    Definition 2

    Proteins in the nucleus or cytoplasm that specifically bind retinoic acid or retinol and trigger changes in the behavior of cells. Retinoic acid receptors, like steroid receptors, are ligand-activated transcription regulators. Several types have been recognized. (NLM, Medical Subject Headings)




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