Health / Medical Topics

    Retroperitoneal Fibrosis

    Definition 1

    A rare, serious disorder characterized by extensive fibrosis in the retroperitoneum. In most cases its etiology is unknown. In some cases it is related to autoimmunity or metastatic cancer. It leads to the entrapment and obstruction of vital retroperitoneal structures including the ureters. (NCI Thesaurus)

    Definition 2

    A slowly progressive condition of unknown etiology, characterized by deposition of fibrous tissue in the retroperitoneal space compressing the ureters, great vessels, bile duct, and other structures. When associated with abdominal aortic aneurysm, it may be called chronic periaortitis or inflammatory perianeurysmal fibrosis. (NLM, Medical Subject Headings)




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