Health / Medical Topics

    S100 calcium binding protein A8

    Pronunciation

    Definition 1

    A protein that is made by many different types of cells and is involved in processes that take place both inside and outside of the cell. It is made in larger amounts in inflammatory diseases such as rheumatoid arthritis, and in some types of cancer. It is being studied as a biomarker for breast cancer. Also called calgranulin A. (NCI Dictionary)

    Definition 2

    Constitutively expressed in epithelial cells and in macrophages during chronic inflammation by human S100A8 Gene (S100 Family), 93-aa 11-kDa homodimeric S100 Calcium Binding Protein A8, containing 2 EF-hand calcium-binding motifs, may interact with intermediate filament components and function in casein kinase inhibition. (NCI Thesaurus)




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