| Health / Medical Topics |
SBIL-2 Transduced Autologous Tumor-Infiltrating Lymphocyte
A population of tumor-infiltrating lymphocytes (TILs) harvested from a patient and transduced with a retroviral vector encoding the gene for interleukin-2 (IL-2). TILs require IL-2 to sustain them when they are transferred back to the patient. By inserting the IL-2 gene into TILs in vitro so that TILs express IL-2 continuously it is possible to provide TIL-sustaining IL-2 in vivo specifically at the site of lymphocyte infiltration, thereby avoiding the toxicity associated with the systemic administration of IL-2. (NCI Thesaurus)
YOU MAY ALSO LIKE
An retroviral vector encoding human IL-2 with potential antineoplastic property. SBIL-2 (Surgery Branch IL-2) can be used to transfect tumor infiltrating lymphocytes,…
Human SBDS wild-type allele is located in the vicinity of 7q11.21 and is approximately 8 kb in length. This allele, which encodes…
This gene plays a role in ribosome formation.
A substance being studied in the treatment of several types of cancer. SB939 blocks the action of an enzyme called histone deacetylase…
A vaccine adjuvant containing CpG 7909, monophosphoryl lipid, and QS-21 with potential antineoplastic and immunostimulatory activities. CpG 7909 is a synthetic 24-mer…
A proprietary oil-in-water emulsion specifically designed for combining protein preparations used in vaccines. SB-AS02B adjuvant contains monophosphoryl lipid A and QS21,…
