Health / Medical Topics

    SEPT6 wt Allele

    Human SEPT6 wild-type allele is located in the vicinity of Xq24 and is approximately 80 kb in length. This allele, which encodes septin-6 protein, plays a role in the regulation of cytoskeletal remodeling. Chromosomal rearrangements of this gene and the MLL gene are associated with acute myelogenous leukemia. (NCI Thesaurus)




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