SH2D1A wt Allele

Human SH2D1A wild-type allele is located within Xq25-q26 and is approximately 27 kb in length. This allele, which encodes SH2 domain protein 1A, plays role in activation, proliferation and differentiation of B and T cells, induces production of IFN gamma, and changes the functional profile of subsets of T cells. Mutations in this gene are associated with X-linked lymphoproliferative (Duncan's) syndrome. (NCI Thesaurus)

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SH2D1A Gene

This gene plays roles in proliferation, differentiation and activation of B and T-cells.

SH2B3 wt Allele

Human SH2B3 wild-type allele is located in the vicinity of 12q24 and is approximately 46 kb in length. This allele, which encodes…

SH2B3 Gene

This gene plays a role in T-cell activation.

SH2B2 wt Allele

Human SH2B2 wild-type allele is located in the vicinity of 7q22 and is approximately 34 kb in length. This allele, which encodes…

SH2B2 Gene

This gene is involved in signal transduction and plays a role in insulin-mediated glucose uptake.

SH2B1 wt Allele

Human SH2B1 wild-type allele is located in the vicinity of 16p11.2 and is approximately 27 kb in length. This allele, which encodes…