SH3-Binding Motif

Typically found in proteins involved in signaling pathways, the SH3-Binding Motif is a peptide sequence that mediates regulated high-affinity physical interaction (binding) with the SH3 (SRC Homology 3) domain in target protein partners. The SH3-binding motif often share proline-rich stretches containing a common PXXP motif. (NCI Thesaurus)

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SH3 Domain-Containing Protein 19

SH3 domain-containing protein 19 (790 aa, ~87 kDa) is encoded by the human SH3D19 gene. This protein is involved in the regulation…

SH3 Domain-Binding Protein 5

SH3 domain-binding protein 5 (455 aa, ~50 kDa) is encoded by the human SH3BP5 gene. This protein is involved in the inhibition…

SH3 Domain-Binding Protein 2

SH3 domain-binding protein 2 (561 aa, ~62 kDa) is encoded by the human SH3BP2 gene. This protein plays a role in intracellular…

SH3 Domain

A region of protein sequence similarity among members of the SRC family of cytoplasmic tyrosine kinases, and other proteins. The SH3 domain…

SH3 and PX Domain-Containing Protein 2A

SH3 and PX domain-containing protein 2A (1133 aa, ~125 kDa) is encoded by the human SH3PXD2A gene. This protein is involved in…

SH3 and Multiple Ankyrin Repeat Domains Protein 3

SH3 and Multiple Ankyrin Repeat Domains Protein 3 (1741 aa, 186 kDa) is a cell communication protein that is encoded by the…