Health / Medical Topics

    SH3GL1 wt Allele

    Human SH3GL1 wild-type allele is located in the vicinity of 19p13.3 and is approximately 40 kb in length. This allele, which encodes endophilin-A2 protein, may play a role in both vesicle formation and endocytosis. A chromosomal translocation t(11;19)(q23;p13) of this gene and the MLL gene is associated with acute myeloid leukemia. (NCI Thesaurus)




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