Health / Medical Topics

    Single-Stranded Conformational Polymorphism

    Definition 1

    A Single-Stranded Conformational Polymorphism consists of nucleotide sequence variation in the same region of DNA between individuals within a species, or between alleles in an individual, that cause partially denatured DNA fragments to take on different conformations as a result of their nucleotide sequences differences. These conformation differences can be detected through various gel-separation techniques. (NCI Thesaurus)

    Definition 2

    A type of mutation scanning; the identification of abnormally-migrating single-stranded DNA segments on gel electrophoresis. (NCI Dictionary)




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