Health / Medical Topics

    Small Inducible Cytokine A17

    Expressed by human CCL17 Gene (Intercrine Beta Family) in thymus, lung, colon, and small intestine and induced by PHA in mononuclear cells and by cytokines in monocytes, secreted 94-aa 10-kD (precursor) Small Inducible Cytokine A17 is an immunoregulatory chemotactic factor for T lymphocytes that binds to CCR4 and CCR8 receptors and is important in inflammatory processes, in thymic T cell development, and in trafficking and activation of mature T cells. (NCI Thesaurus)




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