Health / Medical Topics

    Small Inducible Cytokine A25

    Expressed in thymic and intestinal dendritic cells by CCL25 Gene (Intercrine Beta Family), secreted immunoregulatory 150-aa 17-kD (precursor) Small Inducible Cytokine A25 is a CCR9 receptor agonist and chemotactic for thymocytes, activated macrophages, THP-1 cells, and dendritics cells in inflammatory processes. Two alternatively spliced gene variants encode antagonist isoforms. (NCI Thesaurus)




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