Health / Medical Topics

    Southern Blotting

    Definition 1

    A technique for the detection of specific DNA fragments that have been separated by polyacrylamide-gel electrophoresis, transferred to a nitrocellulose or other type of paper or nylon membrane, and detected by hybridization and visualization with a labeled probe. (NCI Thesaurus)

    Definition 2

    Electrophoresis-based technique used in genetic testing to detect large deletions in DNA that can be missed by PCR-based genetic testing methods. (NCI Dictionary)




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