| Library / English Dictionary |
SPECIFICITY
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
The quality of being specific rather than general
Example:
the specificity of the symptoms of the disease
Classified under:
Nouns denoting attributes of people and objects
Hypernyms ("specificity" is a kind of...):
particularity; specialness (the quality of being particular and pertaining to a specific case or instance)
Derivation:
specific (stated explicitly or in detail)
Sense 2
Meaning:
The quality of being specific to a particular organism
Example:
host specificity of a parasite
Classified under:
Nouns denoting attributes of people and objects
Hypernyms ("specificity" is a kind of...):
particularity; specialness (the quality of being particular and pertaining to a specific case or instance)
Context examples:
MEK 1 and 2 are dual specificity kinases that are essential mediators in the activation of the RAS/RAF/MEK/ERK pathway and are often upregulated in various cancer cells.
(Carbon C 14 Selumetinib, NCI Thesaurus)
The evolution in the diversity of bacterial, fungal, and viral populations identified using mass sequencing techniques revealed the specificity of each of the phases of the process.
(Scientists validate a new technology that transforms sewage sludge into fertilizer more efficiently, University of Granada)
The specificity of a test can be determined by calculating: number of true negative results divided by the sum of true negative results plus number of false positive results.
(Diagnostic Specificity, NCI Thesaurus)
MEK, a dual-specificity threonine/tyrosine kinase that plays a key role in the activation of the RAS/RAF/MEK/ERK signaling pathway, is frequently upregulated in a variety of tumor cell types.
(MEK Inhibitor WX-554, NCI Thesaurus)
Stabilizing hydrophobic zinc finger interactions contribute to DNA binding specificity, homodimerization, and interaction with other proteins.
(Nuclear Receptor Gene, NCI Thesaurus)
The cell keeps its pools of NADH and NADPH isolated biochemically, through the specificity of the enzymes that use and generate these cofactors.
(Oxidative Reactions of the Pentose Phosphate Pathway, NCI Thesaurus/BIOCARTA)
MPA displays high lymphocyte specificity and cytotoxicity because lymphocyte metabolism is highly dependent on both salvage and de novo synthesis of guanine nucleotides.
(Mycophenolate, NCI Thesaurus)
The linkage system in brentuximab vedotin is highly stable in plasma, resulting in cytotoxic specificity for CD30-positive cells.
(Brentuximab vedotin, NCI Thesaurus)
MEK1/2 are dual-specificity threonine/tyrosine kinases that play key roles in the activation of the RAS/RAF/MEK/ERK pathway and are often upregulated in a variety of tumor cell types.
(MEK Inhibitor MEK162, NCI Thesaurus)
A test with high specificity has a low false-positive rate and thus does a good job of correctly classifying unaffected individuals.
(Diagnostic Specificity, NCI Dictionary)
