Health / Medical Topics

    SPP1 wt Allele

    Human SPP1 wild-type allele is located in the vicinity of 4q22.1 and is approximately 8 kb in length. This allele, which encodes osteopontin protein, plays a role in the modulation of both intercellular communication and matrix mineralization. Aberrant expression may be associated with many cancers. (NCI Thesaurus)




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