| Health / Medical Topics |
Squalamine lactate
Pronunciation
Definition 1
A drug that belongs to the family of drugs called angiogenesis inhibitors. It prevents the growth of new blood vessels into a solid tumor. (NCI Dictionary)
Definition 2
The lactate salt form of squalamine, an aminosterol isolated from tissues of the dogfish shark Squalus acanthias. Possessing anti-angiogenic properties, squalamine inhibits the sodium-hydrogen exchanger NHE3, resulting in suppression of endothelial cell proliferation and migration. This agent also has broad-spectrum antimicrobial properties. (NCI Thesaurus)
YOU MAY ALSO LIKE
Human SQSTM1 wild-type allele is located 5q35 and is approximately 32 kb in length. This allele, which encodes sequestosome-1 protein, plays a…
This gene is involved in signal transduction.
Examination under a microscope of cells found in sputum (mucus and other matter brought up from the lungs by coughing). The test…
Mucus and other matter brought up from the lungs by coughing.
A compressed fruiting branch. Spurs are short, stubby, side stems that arise from the main stem where they may bear fruit; they…
Genus of retroviruses which establish persistent, but non pathogenic infections in mammals and primates, including humans, chimpanzees, cattle, and cats. It is…
