SRGAP3/RAF1 Fusion Protein

A fusion protein (931, ~96 kDa) encoded by the SRGAP3/RAF1 fusion gene. This protein is comprised of the first 513 N-terminal amino acids of SLIT-ROBO Rho GTPase-activating protein 3, including the FCH domain, fused to 318 C-terminal amino acids of the RAF proto-oncogene serine/threonine-protein kinase protein, including the protein kinase domain. (NCI Thesaurus)

YOU MAY ALSO LIKE

SRGAP3/RAF1 Fusion Gene

A fusion gene (~3.5 kb) that results from a tandem duplication at chromosome 3p25 which fuses exon 12 of the SRGAP3 gene…

SRGAP3 wt Allele

Human SRGAP3 wild-type allele is located in the vicinity of 3p25.3 and is approximately 382 kb in length. This allele, which encodes…

SRGAP3 Gene

This gene plays a role in GTPase-mediated signaling.

SRF wt Allele

Human SRF wild-type allele is located in the vicinity of 6p21.1 and is approximately 10 kb in length. This allele, which encodes…

SRF Gene

This gene is involved in the regulation of transcription, cell proliferation and differentiation.

SRF Activation Pathway

Serum response factor (SRF) is a transcription factor, which binds to a serum response element (SRE) associated with a variety of genes…