ST5 Protein

ST5 protein contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. (NCI Thesaurus/LocusLink)

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ST5 Gene

This gene plays a role in signal transduction and tumor suppression.

ST2 Gene

Human ST2 gene is located within 11p14.3-p12 and has no known gene product. This locus may play a role in tumor…

ST1481

A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called topoisomerase inhibitors. Also…

ST14 wt Allele

Human ST14 wild-type allele is located within 11q24-q25 and is approximately 51 kb in length. This allele, which encodes suppressor of tumorigenicity…

ST14 Gene

This gene is involved in the activation of proteases and latent growth factors in epithelial membranes.

ST13 wt Allele

Human ST13 wild-type allele is located in the vicinity of 22q13.2 and is approximately 32 kb in length. This allele, which encodes…