Stage 4S Neuroblastoma

Localized primary tumor, as defined for stage 1, 2A, or 2B, with dissemination limited to skin, liver, and/or bone marrow (limited to infants younger than 1 year). Marrow involvement should be minimal (i.e., <10% of total nucleated cells identified as malignant by bone biopsy or by bone marrow aspirate). More extensive bone marrow involvement would be considered stage 4 disease. The results of the MIBG scan, if performed, should be negative for disease in the bone marrow. (cancer.gov) (NCI Thesaurus)

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Stage 4 neuroblastoma

Stage 4 neuroblastoma is divided into stages 4 and 4S. In stage 4, the tumor has spread to distant lymph nodes, the…

Stage 3 neuroblastoma

In stage 3 neuroblastoma, the tumor (1) cannot be completely removed during surgery and has spread from one side of the body…

Stage 2B Neuroblastoma

Localized tumor with or without complete gross excision, with ipsilateral nonadherent lymph nodes positive for tumor. Enlarged contralateral lymph nodes must be…

Stage 2A Neuroblastoma

Localized tumor with incomplete gross excision; representative ipsilateral nonadherent lymph nodes negative for tumor microscopically. (cancer.gov)

Stage 2 neuroblastoma

Stage 2 is divided into stages 2A and 2B. In stage 2A, the tumor is in one area only and not all…

Stage 1 neuroblastoma

Tumor is only found in one area; all of the tumor that can be seen is completely removed during surgery.