Library / English Dictionary

SYNAPTIC

Pronunciation (US):

(GB):

 I. (adjective) 

Sense 1

Meaning:

(neuroscience) of or involving synapses

Classified under:

Relational adjectives (pertainyms)

Pertainym:

synapse (the junction between two neurons (axon-to-dendrite) or between a neuron and a muscle)

Derivation:

synapse (the junction between two neurons (axon-to-dendrite) or between a neuron and a muscle)

Credits

 Context examples: 

This gene plays a role in signal transduction and modulates synaptic transmission.

(AKAP9 Gene, NCI Thesaurus)

This gene is involved in neuronal synaptic activity and RNA interactions.

(NOVA1 Gene, NCI Thesaurus)

This gene plays a role in cell-cell signaling, muscle contraction and synaptic transmission.

(NOS1 Gene, NCI Thesaurus)

The human brain is estimated to include some 86 billion neurons (or nerve cells) and as many as 150 trillion synaptic connections, making it a powerful machine for processing and storing memories.

(Selective amnesia: how rats and humans are able to actively forget distracting memories, University of Cambridge)

Paroxetine binds to the pre-synaptic serotonin transporter complex resulting in negative allosteric modulation of the complex, thereby blocking reuptake of serotonin by the pre-synaptic transporter.

(Paroxetine Mesylate, NCI Thesaurus)

Paroxetine binds to the pre-synaptic serotonin transporter complex resulting in negative allosteric modulation of the complex thereby blocking reuptake of serotonin by the pre-synaptic transporter.

(Paroxetine hydrochloride, NCI Thesaurus)

Cidoxepin may inhibit the reuptake of serotonin and noradrenaline from the synaptic cleft, thereby increasing their activity.

(Cidoxepin, NCI Thesaurus)

The increase in synaptic concentrations of these catecholamines causes behavioral changes including an increase in motor activity, mental alertness and excitement, causes euphoria, and suppresses appetite.

(Chlorphentermine, NCI Thesaurus)

The activation effects of the phenobarbital-receptor-ionophore complex include increased frequency of chloride channel openings, membrane hyperpolarization and ultimately synaptic inhibition and decreased neuronal excitability.

(Phenobarbital, NCI Thesaurus)

This damages nerve cells by blocking their ability to make the proteins needed for synaptic function and leads to the death of neurons in the brain and spinal cord.

(Mechanism behind neuron death in motor neurone disease and frontotemporal dementia discovered, University of Cambridge)