| Library / English Dictionary |
SYSTEMIC
| Pronunciation (US): |  | (GB): | |
I. (adjective)
Sense 1
Meaning:
Affecting an entire system
Example:
a systemic poison
Classified under:
Similar:
general (affecting the entire body)
Context examples:
This often results in systemic action of the agent due to absorption through the nasal mucosa.
(Nasal Route of Administration, NCI Thesaurus)
Upon oral administration of the oral rehydration solution (ORS), water, electrolytes and glucose are absorbed from the gastrointestinal (GI) tract into the systemic circulation.
(Oral Rehydration Solution OS-1, NCI Thesaurus)
The researchers determined that the children with otulipenia might respond to drugs that turned off tumor necrosis factor, a chemical messenger involved in systemic inflammation.
(Researchers discover otulipenia, a new inflammatory disease, NIH)
Pegylated liposomal delivery of irinotecan improves drug penetration into tumors and decreases drug clearance, thereby increasing the duration of exposure while lowering systemic toxicity.
(Pegylated Liposomal Irinotecan, NCI Thesaurus)
Treatment consists of antibiotics to halt the infection, as well as interventions to curb the systemic inflammatory response and restore normal blood pressure.
(New study sheds fresh light on the genetic mechanisms involved in sepsis, the leading cause of death in ICUs, University of Granada)
The introduction of a substance to the mouth or into the gastrointestinal tract by the way of the mouth, usually for systemic action.
(Oral Route of Administration, NCI Thesaurus)
Hepcidin, a peptide hormone that plays a key role in the homeostasis of systemic iron, is upregulated during acute and chronic inflammation in response to cytokines.
(PEG-linked L-RNA Oligonucleotide Hepcidin-targeting Agent NOX-H94, NCI Thesaurus)
Paclitaxel liposome formulation potentially enhances delivery of higher doses of paclitaxel to the target tissues and exhibits lower systemic toxicity.
(Paclitaxel liposome, NCI Thesaurus)
It can cause systemic infections in people with suppressed immune systems.
(beta hemolytic streptococcus group B, NCI Dictionary)
Nisoldipine inhibits the transmembrane influx of extracellular calcium ions into myocardial and vascular smooth muscle cells, causing dilatation of the main coronary and systemic arteries and decreasing myocardial contractility.
(Nisoldipine, NCI Thesaurus)
