TBPL1 wt Allele

Definition 1

Human TBPL1 wild-type allele is located within 6q22.1-q22.3 and is approximately 34 kb in length. This allele, which encodes TATA box-binding protein-like protein 1, plays a role in the regulation of both spermatogenesis and expression of developmental genes. (NCI Thesaurus)

Definition 2

A drug being studied in the treatment of kidney cancer that has spread. It is also being studied in the treatment of other types of cancer and other conditions. TLF increases the activity of dendritic cells (a type of immune cell) to help kill cancer cells. It is a form of human lactoferrin (a protein found in milk, tears, mucus, bile, and some white blood cells) that is made in the laboratory. TLF is a type of recombinant protein and a type of immunomodulatory protein. (NCI Dictionary)

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