Library / English Dictionary

    THEREBY

    Pronunciation (US): Play  (GB): Play

     I. (adverb) 

    Sense 1

    Meaning:

    By that means or because of thatplay

    Example:

    He knocked over the red wine, thereby ruining the table cloth

    Classified under:

    Adverbs

    Credits

     Context examples: 

    As a vitamin K antagonist, acenocoumarol inhibits vitamin K epoxide reductase, thereby inhibiting the reduction of vitamin K and the availability of vitamin KH2.

    (Acenocoumarol, NCI Thesaurus)

    ABT- 751 binds to the colchicine-binding site on beta-tubulin and inhibits the polymerization of microtubules, thereby preventing tumor cell replication.

    (ABT-751, NCI Thesaurus)

    This gene is involved in antigen presentation, a process through which an antigen produced by a cell is displayed on the cell’s outer surface and is thereby “presented” to the immune system.

    (Cellular immunotherapy targets a common human cancer mutation, NIH)

    Velutin is able to inhibit the degradation of the inhibitor of nuclear factor kappa-B (NF-kB), thereby blocking the activation of NF-kB, as well as inhibiting phosphorylation of mitogen-activated protein kinase p38 and JNK.

    (Acai Berry Juice, NCI Thesaurus)

    Thereby, aceglatone may suppress the developments of hormone-dependent cancers mediated through beta-glucuronidase inhibition.

    (Aceglatone, NCI Thesaurus)

    Although its mechanism of action is not fully known, acetarsone may bind to protein-containing sulfhydryl groups located in the parasite, thereby forming lethal As-S bonds.

    (Acetarsol, NCI Thesaurus)

    Upon administration, adalimumab binds to TNF-alpha, thereby preventing its binding to the p55 and p75 TNF cell surface receptors and inhibiting TNF-mediated immune responses.

    (Adalimumab, NCI Thesaurus)

    Upon administration, this vaccine may induce both humoral and cellular immune responses against tumor cells expressing the CEA antigen, thereby resulting in the immune-mediated inhibition of tumor cell proliferation and tumor cell death.

    (Adenoviral Vector Ad5-CEA(6D) Vaccine, NCI Thesaurus)

    Upon intravenous administration, c-Met inhibitor SAR125844 binds to c-Met, thereby disrupting c-Met-mediated signal transduction pathways.

    (MET Tyrosine Kinase Inhibitor SAR125844, NCI Thesaurus)

    MET inhibitor EMD 1204831 selectively binds to Met tyrosine kinase, thereby disrupting MET mediated signal transduction pathways.

    (MET Tyrosine Kinase Inhibitor EMD 1204831, NCI Thesaurus)


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