TLX3 wt Allele

Human TLX3 wild-type allele is located in the vicinity of 5q35.1 and is approximately 3 kb in length. This allele, which encodes T-cell leukemia homeobox protein 3, may play a role in the regulation of transcription. T-cell leukemia is associated with mutation or aberrant expression of the gene and with at least two chromosomal translocations that include the gene. Translocation t(5;14)(q35;q32) fuses this gene and the BCL11B gene and translocation t(5;14)(q35;q11) fuses this gene with the T cell receptor delta locus. (NCI Thesaurus)

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TLX3 Gene

This gene may be involved in transcriptional regulation.

TLX1 wt Allele

Human TLX1 wild-type allele is located in the vicinity of 10q24 and is approximately 7 kb in length. This allele, which encodes…

TLX1 Gene

This gene plays a role in transcriptional regulation and organogenesis. Translocations in the gene are associated with acute T-cell leukemia.

TLR9 wt Allele

Human TLR9 wild-type allele is located in the vicinity of 3p21.3 and is approximately 5 kb in length. This allele, which encodes…

TLR9 Gene

This gene plays a role in innate immunity.

TLR9 Agonist SD-101

A proprietary oligonucleotide with immunostimulatory activity. Immunostimulatory phosphorothiolate oligodeoxyribonucleotide SD-101 targets Toll-Like Receptor 9 (TLR9) found on a specialized subset of dendritic…