| Health / Medical Topics |
Tn Antigen
A protein antigen that is comprised of the monosaccharide N-acetylgalactosamine (GalNAc) bound to serine or threonine by O-linked glycosylation. Aberrant expression of Tn antigen by all blood cell lineages is associated with a rare hematological disorder called Tn-syndrome. Increased expression of this monosaccharide modification is also associated with some cancers and this antigen is being investigated for use as either a biomarker or therapeutic target for these associated malignancies. (NCI Thesaurus)
YOU MAY ALSO LIKE
Human TMTC1 wild-type allele is located in the vicinity of 12p11.22 and is approximately 284 kb in length. This allele, which encodes…
This gene is a mitochondrial integral membrane protein of unknown function.
A fusion gene that results from a chromosomal translocation t(7;21)(p21;q22) which fuses the 5' end of the TMPRRSS2 gene with exon 4…
A fusion gene that results from a genetic translocation event which fuses the 5' end of the androgen-regulated TMPRRSS2 gene with the…
Human TMPRSS2 wild-type allele is located in the vicinity of 21q22.3 and is approximately 51 kb in length. This allele, which encodes…
This gene plays a role in the activation of pathway signaling.
