Transitional Cell Carcinoma

Definition 1

A malignant neoplasm arising from the transitional epithelium, usually affecting the urinary bladder, ureter, or renal pelvis. It may or may not have a papillary configuration. It is graded 1 to 3 or 4 according to the degree of cellular differentiation and architectural patterns. Grade 1 transitional cell carcinoma is histologically benign but it may recur. Transitional cell carcinomas may also affect the upper respiratory tract and the ovaries. (NCI Thesaurus)

Definition 2

A malignant neoplasm arising from transitional epithelium, usually affecting the urinary bladder, ureter, or renal pelvis. (NCI Thesaurus/CDISC)

Definition 3

Cancer that forms in transitional cells in the lining of the bladder, ureter, or renal pelvis (the part of the kidney that collects, holds, and drains urine). Transitional cells are cells that can change shape and stretch without breaking apart. (NCI Dictionary)

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