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TRUNCATED
| Pronunciation (US): |  | (GB): | |
I. (adjective)
Sense 1
Meaning:
Terminating abruptly by having or as if having an end or point cut off
Example:
a truncated pyramid
Synonyms:
truncate; truncated
Classified under:
Similar:
short ((primarily spatial sense) having little length or lacking in length)
Sense 2
Meaning:
Cut short in duration
Example:
an unsatisfactory truncated conversation
Synonyms:
abbreviated; shortened; truncated
Classified under:
Similar:
short (primarily temporal sense; indicating or being or seeming to be limited in duration)
II. (verb)
Sense 1
Past simple / past participle of the verb truncate
Context examples:
The recombinant human megakaryocyte growth and development factor (rHuMGDF) component of this formulation is a nonglycosylated, truncated form of the Mpl ligand.
(PEG Recombinant Human Megakaryocyte Growth and Development Factor, NCI Thesaurus)
MMTV INT3 interruption of NOTCH4 produces a gain-of-function truncated product, containing only the transmembrane and intracellular domains, that has profound consequences for mammary gland development and tumorigenesis.
(Notch4 Protein, NCI Thesaurus)
mRNA Surveillance works within elaborate cellular mechanisms to ensure accurate gene expression by assessing suitable mRNA quality for translation and prevents the synthesis of truncated or aberrant proteins.
(mRNA Surveillance, NCI Thesaurus)
RB94 is a modified, N-terminal truncated form of the full-length protein retinoblastoma gene RB110, and exerts enhanced antitumor activity.
(Liposome-encapsulated RB94 Plasmid DNA Gene Therapy Agent SGT-94, NCI Thesaurus)
A cancer vaccine consisting of a truncated recombinant HER2/neu peptide (dHER2) combined with the immunoadjuvant AS15 with potential immunostimulatory and antineoplastic activities.
(dHER2 Vaccine+AS15 Adjuvant, NCI Thesaurus)
Truncated Bid (tBid) translocates to mitochondria, inducing cytochrome C release, which sequentially activates caspases 9 and 3.
(DR3 and DR4/5 Mediated Apoptosis Pathway, NCI Thesaurus/BIOCARTA)
The CYP2C19*2 allele exhibits a clinically-relevant SNP (c.681G>A) in exon 5 that causes a splicing defect; this alteration results in a truncated cytochrome P450 2C19*2 protein that is enzymatically inactive.
(CYP2C19*2 Allele, NCI Thesaurus)
Deleted in Malignant Brain Tumors 1, encoded by the human DMBT1 gene, is a member of the scavenger-receptor superfamily and likely a truncated form of a receptor for SFTPD.
(Deleted in Malignant Brain Tumors 1, NCI Thesaurus)
Most of these alterations result in a truncated form of the breast cancer type 2 susceptibility protein.
(BRCA2 Gene Mutation, NCI Thesaurus)
Approximately 75% of these alterations result in a truncated form of the breast cancer type 1 susceptibility protein.
(BRCA1 Gene Mutation, NCI Thesaurus)
