Type D Retrovirus

Definition 1

A genus of the family RETROVIRIDAE consisting of oncogenic exogenous retroviruses that contain type D particles. They include the type species, MASON-PFIZER MONKEY VIRUS, isolated from mammary carcinoma and normal tissues in rhesus monkeys, and several other serotypes of simian type D retroviruses (RETROVIRUSES TYPE D, SIMIAN), all of which cause simian AIDS (SAIDS) and other malignancies. The permanent human fibroblast virus (PMFV) is also type D. The core of the type D viruses is the intracytoplasmic type A particle and its mechanism of budding from the cell membrane is similar to the type B oncoviruses. (NLM, Medical Subject Headings)

Definition 2

contains several isolates of exogenous, horizontally transmitted and endogenous viruses of new and old world primates; associated with immunodeficiency diseases. (NIH CRISP Thesaurus)

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