Library / English Dictionary

    VII

    Pronunciation (US): Play  (GB): Play

     I. (noun) 

    Sense 1

    Meaning:

    The cardinal number that is the sum of six and oneplay

    Synonyms:

    7; heptad; septenary; septet; seven; sevener; VII

    Classified under:

    Nouns denoting quantities and units of measure

    Hypernyms ("VII" is a kind of...):

    digit; figure (one of the elements that collectively form a system of numeration)

     II. (adjective) 

    Sense 1

    Meaning:

    Being one more than sixplay

    Synonyms:

    7; seven; vii

    Classified under:

    Adjectives

    Similar:

    cardinal (being or denoting a numerical quantity but not order)

    Credits

     Context examples: 

    A genetic skin disorder caused by mutations in the type VII collagen gene (COL7A1).

    (Epidermolysis Bullosa Dystrophica, NCI Thesaurus)

    The factor is a glycoprotein/phospholipid, which functions as a potent high-affinity transmembrane receptor/cofactor for coagulation factor VII.

    (Coagulation Factor III, NCI Thesaurus)

    This cascade is initiated by the activation of factor X by TF and factor VII.

    (Extrinsic Prothrombin Activation Pathway, NCI Thesaurus/BIOCARTA)

    This prevents the activation of vitamin K-dependent coagulation factors II, VII, IX, and X and the anticoagulant proteins C and S, which abrogates both thrombin production and thrombus formation.

    (Phenprocoumon, NCI Thesaurus)

    A fusion protein of clotting factor VII with the Fc portion of an IgG1 antibody.

    (FVII Icon, NCI Thesaurus)

    The vitamins K are essential for blood coagulation as it is necessary for the hepatic synthesis of the coagulation factors II, VII, IX, and X; deficiency results in a bleeding diathesis.

    (Phytonadione, NCI Thesaurus)

    A canal in the petrous region of the temporal bone that serves as the passage for cranial nerves (mainly the VII and VIII cranial nerves) towards the middle and inner ear.

    (Internal Auditory Canal, NCI Thesaurus)

    A condition characterized as a coagulation disturbance in newborns due to vitamin K deficiency resulting in impaired production of coagulation factors II, VII, IX, and X, and proteins C and S by the liver.

    (Hemorrhagic Disease of Newborn, NCI Thesaurus)

    This prevents gamma carboxylation of glutamic acid residues near the N-terminals of the vitamin K-dependent clotting factors, including factor II, VII, IX, and X and anticoagulant proteins C and S. This prevents their activity and thus thrombin formation.

    (Acenocoumarol, NCI Thesaurus)

    Anisindione interferes with the vitamin K-dependent hepatic synthesis of active clotting factors by inhibiting the reduction of vitamin K. This leads to an inhibition of gamma-carboxylation of glutamic acid residues to gamma-carboxyglutamic acid in clotting factors II, VII, IX and X. The consequential effects of this inhibition include a reduced activity of these clotting factors and prolonged blood clotting time.

    (Anisindione, NCI Thesaurus)


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