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X-LINKED
| Pronunciation (US): |  | (GB): | |
I. (adjective)
Sense 1
Meaning:
Relating to genes or characteristics or conditions carried on the X chromosome
Example:
an X-linked mutation
Classified under:
Relational adjectives (pertainyms)
Pertainym:
X chromosome (the sex chromosome that is present in both sexes: singly in males and doubly in females)
Context examples:
Mutations in the gene are associated with both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.
(NR0B1 wt Allele, NCI Thesaurus)
An X-linked recessive inherited disorder caused by mutations in the G6PD gene.
(Glucose-6-phosphate dehydrogenase deficiency, NCI Thesaurus)
Translocations and mutations involving the gene are associated with X-linked infantile spasm syndrome 2.
(CDKL5 wt Allele, NCI Thesaurus)
An X-linked, inherited lysosomal storage disease caused by the deficiency of the enzyme iduronate sulfatase that is responsible for the degradation of mucopolysaccharides.
(Hunter Syndrome, NCI Thesaurus)
This assay was used to detect X chromosomal inactivation for diagnosis of X-linked conditions, ie.
(HUMARA Assay, NCI Thesaurus)
An X-linked inherited bleeding disorder caused by deficiency of the coagulation factor IX.
(Hemophilia B, NCI Thesaurus)
Mutation of the gene is associated with X-linked agammaglobulinemia type 1.
(BTK wt Allele, NCI Thesaurus)
A form of AMELOGENESIS IMPERFECTA characterized by incomplete formation of the dental enamel and transmitted as an X-linked or autosomal dominant trait.
(Enamel Hypoplasia, NLM, Medical Subject Headings)
Deletions in the alpha 5 gene that extend into the alpha 6 gene result in diffuse leiomyomatosis accompanying the X-linked Alport syndrome caused by the deletion in the alpha 5 gene.
(Collagen IV (Alpha 6), NCI Thesaurus)
AEG35156 selectively blocks the cellular expression of X-linked inhibitor of apoptosis protein (XIAP), a pivotal inhibitor of apoptosis that is overexpressed in many tumors.
(AEG35156, NCI Thesaurus)
