| Health / Medical Topics |
1-Phosphatidylinositol-4,5-Bisphosphate Phosphodiesterase Beta 3
Expressed in many tissues by human PLCB3 Gene, 1234-aa 139-kDa membrane-bound Phospholipase C Beta 3 contains a catalytic PI-PLC X-box domain, a catalytic PI-PLC Y-box domain, and a C2 domain. Activated in response to stimulation by hormones, growth factors, neurotransmitters, and other ligands, PLCB3 is a key enzyme in initiating receptor-mediated signal transduction by mediating production of DAG and IP3 second messengers. (NCI Thesaurus)
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