ADAM12 wt Allele

Human ADAM12 wild-type allele is located in the vicinity of 10q26.3 and is approximately 373 kb in length. This allele, which encodes disintegrin and metalloproteinase domain-containing protein 12, is involved in the modulation of cell adhesion, signaling and proteolysis. (NCI Thesaurus)

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ADAM12 Gene

This gene plays a role in the regulation of proteolysis.

ADAM11 wt Allele

Human ADAM11 wild-type allele is located in the vicinity of 17q21.3 and is approximately 21 kb in length. This allele, which encodes…

ADAM11 Gene

This gene plays a role in cell-cell and cell-matrix interactions.

ADAM10 wt Allele

Human ADAM10 wild-type allele is located in the vicinity of 15q22 and is approximately 155 kb in length. This allele, which encodes…

ADAM10 Gene

This gene plays a role in the regulation of protein cleavage.

ADAM Type Metalloprotease Domain

ADAMs are transmembrane proteins containing both a disintegrin and a metalloprotease domain. Two thirds of the proteins with an ADAM type metalloprotease…