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AGONIST
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
(biochemistry) a drug that can combine with a receptor on a cell to produce a physiological reaction
Classified under:
Nouns denoting man-made objects
Hypernyms ("agonist" is a kind of...):
drug (a substance that is used as a medicine or narcotic)
Domain category:
biochemistry (the organic chemistry of compounds and processes occurring in organisms; the effort to understand biology within the context of chemistry)
Sense 2
Meaning:
A muscle that contracts while another relaxes
Example:
when bending the elbow the biceps are the agonist
Classified under:
Hypernyms ("agonist" is a kind of...):
antagonistic muscle ((physiology) a muscle that opposes the action of another)
Sense 3
Meaning:
Someone involved in a contest or battle (as in an agon)
Classified under:
Hypernyms ("agonist" is a kind of...):
contestant (a person who participates in competitions)
Antonym:
antagonist (someone who offers opposition)
Derivation:
agonistic (of or relating to the athletic contests held in ancient Greece)
agony (intense feelings of suffering; acute mental or physical pain)
agony (a state of acute pain)
Sense 4
Meaning:
The principal character in a work of fiction
Synonyms:
Classified under:
Nouns denoting people
Hypernyms ("agonist" is a kind of...):
character; fictional character; fictitious character (an imaginary person represented in a work of fiction (play or film or story))
Hyponyms (each of the following is a kind of "agonist"):
antihero (a protagonist who lacks the characteristics that would make him a hero (or her a heroine))
Derivation:
agony (intense feelings of suffering; acute mental or physical pain)
Context examples:
The sulfate salt form of metaproterenol, a short-acting and selective sympathomimetic beta-receptor agonist with bronchodilator activity.
(Metaproterenol Sulfate, NCI Thesaurus)
The chloride salt form of methacholine, a direct-acting cholinergic muscarinic agonist with bronchoconstrictive, miotic, vasodilator, and cardiac vagomimetic activity.
(Methacholine Chloride, NCI Thesaurus)
A liquid, oromucosal formulation containing a muscarinic agonist with potential anti-xerostomia activity.
(Muscarinic Agonist APD515, NCI Thesaurus)
The hydrochloride salt form of nalbuphine, a synthetic phenanthrene opioid with opiate agonist and antagonist effects, used to treat moderate to severe pain and provide preoperative and postoperative analgesia and sedation.
(Nalbuphine Hydrochloride, NCI Thesaurus)
Any agent that binds to or interferes with binding to any of the opioid receptor subtypes, thereby blocking the actions of opioid agonists.
(Opiate Antagonist, NCI Thesaurus)
The orally available hydrochloride salt of the opioid agonist noscapine, a phthalideisoquinoline alkaloid derived from the opium poppy Papaver somniferum, with mild analgesic, antitussive, and potential antineoplastic activities.
(Noscapine Hydrochloride, NCI Thesaurus)
A sulfonate-based salt form of a trimebutine derivative, an orally available, peripherally-acting opioid agonist and muscarinic antagonist, with potential visceral analgesic activity.
(Opioid Agonist GIC-1001, NCI Thesaurus)
Opioid receptor agonists mimic the actions of endogenous opioid peptides.
(Opioid Receptor Agonist, NCI Thesaurus)
A water soluble, orally available, dual peroxisome proliferator-activated receptor (PPAR) alpha and gamma agonist with hypoglycemic activity.
(Oxeglitazar, NCI Thesaurus)
Furthermore, agonist receptors activate calcium channels of the endoplasmic reticulum (ER) via phospholipase C and inositol 1,4,5-trisphosphate.
(Nitric Oxide Pathway, NCI Thesaurus/BIOCARTA)
