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ANTAGONIST
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I. (noun)
Sense 1
Meaning:
A drug that neutralizes or counteracts the effects of another drug
Classified under:
Nouns denoting man-made objects
Hypernyms ("antagonist" is a kind of...):
drug (a substance that is used as a medicine or narcotic)
Hyponyms (each of the following is a kind of "antagonist"):
estrogen antagonist; tamoxifen (an antagonist for estrogen that is used in the treatment of breast cancer)
narcotic antagonist (an antagonist used to counteract the effects of narcotics (especially to counteract the depression of respiration))
Antonym:
synergist (a drug that augments the activity of another drug)
Derivation:
antagonism ((biochemistry) interference in or inhibition of the physiological action of a chemical substance by another having a similar structure)
antagonistic (used especially of drugs or muscles that counteract or neutralize each other's effect)
Sense 2
Meaning:
A muscle that relaxes while another contracts
Example:
when bending the elbow the triceps are the antagonist
Classified under:
Hypernyms ("antagonist" is a kind of...):
antagonistic muscle ((physiology) a muscle that opposes the action of another)
Derivation:
antagonistic (used especially of drugs or muscles that counteract or neutralize each other's effect)
Sense 3
Meaning:
Someone who offers opposition
Synonyms:
adversary; antagonist; opponent; opposer; resister
Classified under:
Hypernyms ("antagonist" is a kind of...):
individual; mortal; person; somebody; someone; soul (a human being)
Hyponyms (each of the following is a kind of "antagonist"):
dueler; duelist; dueller; duellist (a person who fights duels)
enemy; foe; foeman; opposition (an armed adversary (especially a member of an opposing military force))
Luddite (any opponent of technological progress)
withstander (an opponent who resists with force or resolution)
Instance hyponyms:
Antichrist ((Christianity) the adversary of Christ (or Christianity) mentioned in the New Testament; the Antichrist will rule the world until overthrown by the Second Coming of Christ)
Antonym:
agonist (someone involved in a contest or battle (as in an agon))
Derivation:
antagonism (an actively expressed feeling of dislike and hostility)
antagonism (the relation between opposing principles or forces or factors)
antagonism (a state of deep-seated ill-will)
antagonistic (indicating opposition or resistance)
Context examples:
Amlexanox also acts as a leukotriene D4 antagonist and a phosphodiesterase inhibitor.
(Amlexanox, NCI Thesaurus)
This agent is also a selective human adenosine A3 receptor antagonist.
(Aminothiadiazole, NCI Thesaurus)
Alvimopan is a selective and competitive antagonist at mu-opioid receptors, found in myenteric and submucosal neurons and the immune cells of the lamina propria in the human gut.
(Alvimopan, NCI Thesaurus)
A long-acting calcium channel antagonist, Amlodipine inhibits transmembrane calcium influx into vascular smooth muscle.
(Amlodipine Besylate/Benazepril Hydrochloride, NCI Thesaurus)
It is a type of interleukin receptor antagonist.
(Anakinra, NCI Dictionary)
A C-C Chemokine Receptor Type 5 (CCR5) antagonist with activity against the human immunodeficiency virus, HIV-1.
(Ancriviroc, NCI Thesaurus)
A recombinant human nonglycosylated interleukin-1 (IL-1) receptor antagonist with potential antineoplastic activity.
(Anakinra, NCI Thesaurus)
The MXI1 protein family functions as potent antagonists of MYC oncoproteins.
(mSin3, NCI Thesaurus)
A non-selective beta-adrenergic antagonist with antihypertensive and antiarrhythmic activities.
(Nadolol, NCI Thesaurus)
I saw him look hard at his antagonist, and as he did so, his hands and his jaw dropped together.
(Rodney Stone, by Sir Arthur Conan Doyle)
