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AMPUTATION
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A surgical removal of all or part of a limb
Classified under:
Nouns denoting acts or actions
Hypernyms ("amputation" is a kind of...):
operation; surgery; surgical operation; surgical procedure; surgical process (a medical procedure involving an incision with instruments; performed to repair damage or arrest disease in a living body)
Derivation:
amputate (remove surgically)
Sense 2
Meaning:
A condition of disability resulting from the loss of one or more limbs
Classified under:
Nouns denoting stable states of affairs
Hypernyms ("amputation" is a kind of...):
disability; disablement; handicap; impairment (the condition of being unable to perform as a consequence of physical or mental unfitness)
Derivation:
amputate (remove surgically)
Context examples:
Other treatments may include amputation, chemotherapy, and radiation therapy.
(Bone Cancer, NIH: National Cancer Institute)
After tail amputation, ROCs migrate from the body to the wound and secrete a cocktail of growth factors that coordinate the response of tissue precursor cells.
(Scientists find new type of cell that helps tadpoles’ tails regenerate, University of Cambridge)
It may result in the formation of constriction rings around the digits and upper and lower extremities, swelling of the extremities and congenital amputations.
(Amniotic Band Syndrome, NCI Thesaurus)
This is defined as any one of the following: Claudication, either with exertion or at rest, amputation for arterial vascular insufficiency, vascular reconstruction, bypass surgery, or percutaneous intervention to the extremities, documented aortic aneurysm with or without repair, vascular angiography demonstrating a 50% or greater stenosis of a major peripheral arterial vessel, positive noninvasive test for peripheral arterial disease, including an ankle-brachial index less than or equal to 0.9, ultrasound, magnetic resonance or computed tomography imaging demonstrating a 50% or greater stenosis of a major peripheral arterial vessel.
(Peripheral Arterial Disorder, NCI Thesaurus/CDISC)
Amputation for arterial vascular insufficiency; 3.
(History of Peripheral Vascular Disease, NCI Thesaurus)
People can lose all or part of an arm or leg for a number of reasons. Common ones include: • Circulation problems from atherosclerosis or diabetes. They may cause you to need an amputation. • Traumatic injuries, including from traffic accidents and military combat • Cancer • Birth defects
(Artificial Limbs, NIH)
For the experimental and sham group, they sutured the device on the frogs immediately after limb amputation.
(Scientists Help Frogs to Regenerate Their Limbs with Bioreactor Device, The Titi Tudorancea Bulletin)
Scientists have designed a device for testing 'electroceuticals,' or cell-stimulating therapies with induce partial hindlimb regeneration in adult aquatic African clawed frogs (Xenopus laevis) by 'kick-starting' tissue repair at the amputation site.
(Scientists Help Frogs to Regenerate Their Limbs with Bioreactor Device, The Titi Tudorancea Bulletin)
RNA sequencing and transcriptome analysis revealed that the bioreactor had altered the gene expression occurring in cells at the amputation site.
(Scientists Help Frogs to Regenerate Their Limbs with Bioreactor Device, The Titi Tudorancea Bulletin)
