APC8015F

Definition 1

A vaccine made from immune system cells taken from a patient with prostate cancer and frozen for future use. The cells are treated in the laboratory with a growth factor attached to a protein called prostatic-acid phosphatase (PAP), which is found on prostate cancer cells. When APC8015F is injected into the patient, it may cause T cells (a type of white blood cell) to kill tumor cells that have PAP on them. (NCI Dictionary)

Definition 2

A cell-based vaccine composed of previously frozen autologous antigen-presenting peripheral blood mononuclear cells (enriched for a dendritic cell fraction) that have been exposed to a recombinant protein consisting of granulocyte-macrophage colony-stimulating factor (GM-CSF) fused to prostatic-acid phosphatase (PAP), a protein expressed by prostate cancer cells. Upon administration, the vaccine may stimulate an antitumor T-cell response against tumor cells expressing PAP. (NCI Thesaurus)

YOU MAY ALSO LIKE

APC8015

A drug used to treat prostate cancer that has spread. It is made from immune system cells collected from a patient with…

APC2 wt Allele

Human APC2 wild-type allele is located in the vicinity of 19p13.3 and is approximately 23 kb in length. This allele, which encodes…

APC2 Gene

This gene is involved in signal transduction and cell cycle regulation.

APC wt Allele

Human APC wild-type allele is located within 5q21-q22 and is approximately 108 kb in length. This allele, which encodes adenomatosis polyposis coli…

APC vaccine

A vaccine made of antigens and antigen-presenting cells (APCs). APCs boost an immune response by presenting antigens on their surfaces to other…

APC Gene

This gene plays a role in signal transduction. It is involved in both adhesion and migration of cells.