Medicine

Si padece de enfermedad de las arterias coronarias, las arterias de su corazón están estrechas o bloqueadas por un material pegajoso llamado… »
Procedimiento para agrandar la abertura de un vaso sanguíneo que se ha vuelto estrecho u obstruido por una placa (acumulación de grasa… »
A procedure to enlarge the opening in a blood vessel that has become narrowed or blocked by plaque (a buildup of fat… »
A measurement of angiopoietin 1 present in a sample. »
Angiopoietin-1 (498 aa, ~58 kDa) is encoded by the human ANGPT1 gene. This protein is involved in both signal transduction and… »
Angiopoietin-1 receptor (1124 aa, ~126 kDa) is encoded by the human TEK gene. This protein is involved in angiopoietin signaling, tyrosine phosphorylation… »
Encoded by Human ANGPT2 Gene, Angiopoietin 2 is a 496-amino acid 57 kD (precursor) homodimeric secreted protein that contains a fibrinogen-like… »
Angiopoietin-4 (503 aa, ~57 kDa) is encoded by the human ANGPT4 gene. This protein plays a role in both vascular development and… »
Angiopoietin-related protein 1 (491 aa, ~57 kDa) is encoded by the human ANGPTL1 gene. This protein is involved in the regulation of… »
Angiopoietin-related protein 4 (406 aa, ~45 kDa) is encoded by the human ANGPTL4 gene. This protein plays a role in the modulation… »
A type of cancer that begins in the cells that line blood vessels or lymph vessels. Cancer that begins in blood vessels… »
Tipo de cáncer que comienza en las células que revisten los vasos sanguíneos o los vasos linfáticos. El cáncer que comienza en… »
An angiosarcoma that develops in association with long standing lymphedema. »
An angiosarcoma arising from the skin of the arm following radical mastectomy and resulting lymphedema. »
The flowering seed plants, as differentiated from gymnosperms, the non-flowering seed plants. »
A protein normally made by the body. It can also be made in the laboratory, and is being studied in the treatment… »
Proteína que el cuerpo elabora habitualmente. También se puede producir en el laboratorio y está en estudio para el tratamiento de… »
Expressed in liver by human AGT Gene (Serpin Family), secreted 485-aa 53-kDa Angiotensinogen is cleaved by renin (in response to lowered blood… »
Fetal embryopathy associated with maternal angiotensis converting enzyme (ACE) inhibitor use during pregnancy that may include fetal acute renal failure, growth restriction,… »
The determination of the amount of angiotensin converting enzyme present in a sample. »
The determination of the amount of angiotensin I hormone present in a sample. »
The determination of the amount of angiotensin II hormone present in a sample. »
A class of agents that act by selectively inhibiting angiotensin II receptor activation in the renin-angiotensin-aldosterone system. Angiotensin II receptor antagonists bind… »
A process that involves the non-covalent binding of angiotensin II to an angiotensin receptor family protein. These interactions are involved in signaling… »
Ang II binding to AT1-R triggers the activation of Ca2+ signaling and PKC. The signal is then transmitted to Pyk2 and to… »
Angiotensin receptor 2 (363 aa, 41 kD) is a cell fate protein that is encoded by the human AGTR2 gene and has… »
Angiotensin-2 (8 aa, ~1 kDa) is encoded by the human AGT gene. This protein is involved in vasoconstriction, heart rate and renal… »
Angiotensin-converting enzyme (1306 aa, ~150 kDa) is encoded by the human ACE gene. This protein plays a role in the hydrolysis of… »
Angiotensin-converting enzyme 2 (805 aa, ~92 kDa) is encoded by the human ACE2 gene. This protein plays a role in both vasodilation… »
Cardiovascular diseases are predicted to be the most common cause of death worldwide by 2020. The major regulator of blood pressure… »
A drug that is used to lower blood pressure. An angiotensin-converting enzyme inhibitor is a type of antihypertensive agent. Also called ACE… »
Sustancia en estudio para el tratamiento de varios tipos de cáncer. La angiotensina terapéutica-(1-7) es una hormona que se produce en el… »
The determination of the amount of angiotensinogen hormone present in a sample. »
Angiotropin is a potent angiogenesis factor isolated from the serum-free media of cultured, lectin-activated peripheral monocytes. (from Arch Surg 1989;124:693-8). Angiotropin is… »
A substance being studied in the treatment of cancer. Angiozyme is a special type of RNA made in the laboratory. It stops… »
Sustancia en estudio para el tratamiento de cáncer. Angiozyme es un tipo especial de ARN producido en el laboratorio. Impide que se… »
The inclination of one line to another or the plane of one object to another. »
A form of glaucoma in which the intraocular pressure increases because the angle of the anterior chamber is blocked and the aqueous… »
This gene plays a role in blood vessel maturation and stability. »
Human ANGPT1 wild-type allele is located within 8q22.3-q23 and is approximately 249 kb in length. This allele, which encodes angiopoietin-1 protein, plays… »
This gene is involved in vascular remodeling. »
Human ANGPT2 wild-type allele is located in the vicinity of 8p23.1 and is approximately 64 kb in length. This allele, which encodes… »
This gene plays a role in both vascular development and angiogenesis. »
Human ANGPT4 wild-type allele is located in the vicinity of 20p13 and is approximately 44 kb in length. This allele, which encodes… »
This gene is involved in the regulation of hematopoietic stem cells. »
Human ANGPTL1 wild-type allele is located in the vicinity of 1q25.2 and is approximately 22 kb in length. This allele, which encodes… »
This gene plays a role in signaling. »
Human ANGPTL4 wild-type allele is located in the vicinity of 19p13.3 and is approximately 10 kb in length. This allele, which encodes… »
A metric unit of length equal to 10E-10 meter or 0.1 nanometer. »
A trichothecene mycotoxin and potent teratogen. Anguidine inhibits initiation of protein synthesis, resulting in the death of rapidly proliferating cells. Anguidine… »
Terminal branch of the facial artery with distribution to the side of the nose. »
Inflammation of the skin at the corners of the mouth characterized by redness, fissures or crusts. »
The portion of the brain located in the parietal lobe that plays a role in intersensory processing, language comprehension, and cognition. … »
A type of pregnancy which starts with the embryo in the interstitial section of the fallopian tube, which then grows into the… »
An extract made from the fruit of the chaste tree (Vitex agnus-castus) found in parts of Asia and Europe. It is claimed… »
An inability to experience pleasure. »
A rare genetic disorder characterized by mutations in the gene encoding ectodysplasin A. It results in abnormalities in the morphogenesis of the… »
Medicamento contra el cáncer que es un tipo de inhibidor mitótico. »
A tricarboxylic acid found in citrus fruits. Citric acid is used as an excipient in pharmaceutical preparations due to its antioxidant… »
The anhydrous form of D-glucose, a natural monosaccharide and carbohydrate. Dextrose serves to replenish lost nutrients and electrolytes. The agent provides metabolic… »
An anticancer drug that belongs to the family of drugs called mitotic inhibitors. »
A drug that is used to treat infections caused by fungi. It belongs to the family of drugs called antifungals. »
Medicamento que se usa en el tratamiento de infecciones ocasionadas por hongos. Es un tipo de antifúngico. »
An opioid receptor agonist belonging to the piperidine class with analgesic activity. By binding to and activating opioid receptors in the central… »
The hydrochloride salt form of anileridine, an opioid receptor agonist belonging to the piperidine class with analgesic activity. By binding to and… »
An alkylating mustard with antineoplastic activity. Aniline mustard forms covalent linkages with nucleophilic centers, resulting in depurination, base miscoding and strand scission,… »
A living organism that has membranous cell walls, requires oxygen and organic foods, and is capable of voluntary movement, as distinguished from… »
A shared facility which maintains a breeding stock of animals in a disease-free state. »
Wild animals usually avoid people. They might attack, however, if they feel threatened, are sick, or are protecting their young or… »
The production of concentrated proteins from animal plasma during a protein purification process. »
A coded value specifying a group of animals presumably related by descent from common ancestors and visibly similar in most characters. … »
An animal model which develops cancer or can be used to generate a model that develops cancer. »
Pigmented animal hemisphere of the amphibian blastula. »
A group of animals of the same species that are living, or being housed together. »
En un estudio, es un animal que no recibe el tratamiento que se está probando. La comparación entre la salud de los… »
A textual or media-based representation of the animal. »
Animal diseases that people can catch are called zoonoses. Many diseases affecting humans can be traced to animals or animal… »
An area intended to confine animals. »
The study of genetic traits in animals. »
The science of breeding and caring for farm animals. »
An animal with a disease either the same as or like a disease in humans. Animal models are used to study the… »
Animal disease whose pathologic mechanisms are sufficiently similar to those of a human disease for the animal disease to serve as a… »
The Animal Models Service Shared Resource is primarily dedicated to the production, development and characterization of biomedical relevant animal models and species… »
A group of presumed common ancestry with clear-cut physiological but usually not morphological distinctions. »
Animal Pharmacology Shared Resource provides support and expertise to Cancer Center investigators in evaluation of the pharmacological effects of drug candidates in… »
Specifies whether the anatomical parts of the body involved in reproduction are missing. »
Indicates that a product is derived from an animal. »
A coded value specifying one of the basic units of biological classification and taxonomic rank that specifies a group of organisms that… »
A laboratory experiment using animals to study the development and progression of diseases. Animal studies also test how safe and effective new… »
The use of animals for testing the safety and efficacy of drugs or treatments. »
Any method or technique that eliminates the use of animals in experiments, research, and testing. »
An animal pathogen that is a virus. »
A type of therapy that uses dogs or other pets to improve the physical and mental health of patients with certain acute… »
Any substance or product derived from an animal. »
Anion exchange protein 3 (1232 aa, ~136 kDa) is encoded by the human SLC4A3 gene. This protein is involved in chloride/bicarbonate exchange… »
The determination of the concentrations of anions, such as chloride and bicarbonate, subtracted from the concentration of cations, such as sodium and… »
Anion Transporter Binding involves temporary non-covalent interaction of a molecule through intermolecular physical forces of attraction with an anion transporter protein that… »
A disorder in which a person is born without part or all of the iris (colored tissue at the front of the… »
Trastorno por el que una persona nace sin una parte del iris (tejido de color en el frente del globo ocular)… »
A characteristic of a medicinal product, specifying that its most predominant agreeable savor detected by the unified sensation of taste and olfactory… »
An essential oil derived from Pimpinella anisum. »
A synthetic indanedione anticoagulant. Anisindione interferes with the vitamin K-dependent hepatic synthesis of active clotting factors by inhibiting the reduction of vitamin… »
The determination of the number of anisocytes present in a sample. »
The presence of erythrocytes with excessive variation in size in the blood. »
A test result indicating the presence of red cells of various sizes and shapes in the peripheral blood. »
The property of being anisotropic, having a different value when measured in different directions. »
This gene plays a role in red blood cell morphology. »
Human ANK1 wild-type allele is located in the vicinity of 8p11.1 and is approximately 243 kb in length. This allele, which encodes… »
Traumatic or pathological injury to the ankle joint in which the continuity of an ankle bone is broken. Symptoms include pain, swelling,… »
Your ankle bone and the ends of your two lower leg bones make up the ankle joint. Your ligaments, which connect bones… »
Harm or hurt to the ankle or ankle joint usually inflicted by an external source. »
A gliding joint between the distal ends of the tibia and fibula and the proximal end of the talus. »
The skin that surrounds the tissues of the ankle joint. »
The ratio of ankle systolic pressure to brachial systolic pressure, used to assess arterial insufficiency in the lower extremities. »
This gene may play a role in breast-specific transcription. »
Human ANKRD30A wild-type allele is located in the vicinity of 10p11.21 and is approximately 122 kb in length. This allele, which encodes… »
An autoimmune chronic inflammatory disorder characterized by inflammation in the vertebral joints of the spine and sacroiliac joints. It predominantly affects young… »
Ankyrin Repeats are tandem modules of about 33 amino acids. The conserved domain structure has been described as side-by-side anti-parallel alpha helices… »
Ankyrin repeat and BTB/POZ domain-containing protein 2 (839 aa, ~93 kDa) is encoded by the human ABTB2 gene. This protein may play… »
Ankyrin repeat domain-containing protein 30A (1397 aa, ~159 kDa) is encoded by the human ANKRD30A gene. This protein is involved in the… »
Ankyrin-1 (1881 aa, ~206 kDa) is encoded by the human ANK1 gene. This protein plays a role in the determination of red… »
An aggressive (fast-growing) disease in which too many myeloblasts (immature white blood cells that are not lymphoblasts) are found in the bone… »
This gene is involved in cytokinesis. »
Human ANLN wild-type allele is located within 7p15-p14 and is approximately 64 kb in length. This allele, which encodes actin-binding protein anillin,… »
The hydrochloride salt form of anlotinib, a receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic and anti-angiogenic activities. Upon administration, anlotininib targets… »
The Ann Arbor system classifies lymphoma into four stages based on anatomic lymph nodal group involvement. Disease confined to one nodal group… »
A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called anthracycline antibiotics. … »
A liposome-encapsulated form of the semi-synthetic doxorubicin analogue annamycin with antineoplastic activity. Annamycin intercalates into DNA and inhibits topoisomerase II, resulting in… »
Annexin A2 (339 aa, ~39 kDa) is encoded by the human ANXA2 gene. This protein is involved in ligand binding, signal transduction… »
Encoded by human Annexin A5 Gene, Annexin A5 is a 35 kD 320-amino acid monomeric placental protein similar to PP4-X that contains… »
Annexin VIII belongs to the family of Ca (2+) dependent phospholipid binding proteins (annexins), and has a high 56% identity to annexin… »
A common name for the tropical tree Annona muricata whose tissues contain annonaceous acetogenins, compounds with antineoplastic activity. Annonaceous acetogenins, derivatives… »
A concise, detailed, description record of cell specimen(s) or tissues for clinical and laboratory applications. The information recorded contains explanatory guidelines or… »
An explanatory or critical comment, or other in-context information (e.g., pattern, motif, link), that has been associated with data or other types… »
A set of annotations, or comments about an idea, subject or item. »
Defines the type of annotation (e.g., direct, mapped, transitive closure). »
A sensation of discomfort or distress that is bothersome and irritating. »
Occurring or done each year. »
Measures the change in rate over time by taking the number of occurrences for the current year, subtracting the number of occurrences… »
Stability data submitted to an annual report or update to an approved application. »
Transmittal of Annual Reports for Drugs and Biologics for Human Use (21 CFR 314.81) »
A once yearly checking for disease in the absence of symptoms. »
A ring-shaped skin finding with clear central area. »
A rare congenital abnormality in which the duodenum is surrounded by a ring of pancreatic tissue. It may result in constriction of… »
A marital status in which a voidable marriage is legally declared null and void, as though it never existed. Specific grounds for… »
A device designed to indicate which electrical circuit is actively receiving current. »
Abertura del recto que va hacia la parte exterior del cuerpo. »
The line between the simple columnar epithelium of the rectum and the stratified epithelium of the anal canal. »
Any apoptotic process triggered by inadequate or inappropriate adherence to substrate, such as may occur after disruption of the interactions between normal… »
La palabra craneofacial es un término médico que está relacionado con los huesos del cráneo y de la cara. Las anomalías craneofaciales… »
A language dysfunction characterized by the inability to name people and objects that are correctly perceived. The individual is able to describe… »
Anonymised data and samples are initially single or double coded but the link between the subjects identifiers and the unique code(s) are… »
Having no known name or identity or known source. »
Anonymous data and samples are never labelled with personal identifiers and therefore there is no potential to trace back genomic data and… »
A rare congenital abnormality characterized by the complete absence of ocular tissue in the orbit. »
A pathologic tract that connects an opening in the anal canal to the perianal skin. In the vast majority of cases there… »
An infectious process affecting the anal area and the rectum. »
An abnormal loss of the appetite for food. Anorexia can be caused by cancer, AIDS, a mental disorder (i.e., anorexia nervosa), or… »
Pérdida anormal del apetito por las comidas. La causa de la anorexia puede ser el cáncer, el SIDA, un trastorno mental (por… »
Trastorno de la alimentación caracterizado por un temor intenso de aumentar de peso, un rechazo a mantener un peso normal y una… »
An eating disorder marked by an intense fear of gaining weight, a refusal to maintain a healthy weight, and a distorted body… »
Any substance that induces loss of appetite to prevent weight gain and achieve weight loss. »
Inability to achieve orgasm. »
Que no es normal. Describe un estado, una afección o un comportamiento que no son habituales o que son diferentes de lo… »
Anosmin-1 (680 aa, ~76 kDa) is encoded by the human KAL1 gene. This protein may play a role in cellular adhesion and… »
The absence of ovulation. »
Absence or reduction of oxygen in body tissue. »
This gene plays a regulatory role in the propagation of pro-apoptotic events. »
Human ANP32B wild-type allele is located in the vicinity of 9q22.32 and is approximately 33 kb in length. This allele, which encodes… »
This gene is involved in tumor suppression. »
Encoded by human ANP32C Gene, 234-amino acid 27 kD PP32R1 Protein (PP32 Family) shares approximately 90% amino acid sequence identity with tumor… »
Human ANP32C wild-type allele is located in the vicinity of 4q32.3 and is approximately 1 kbin length. This allele, which encodes acidic… »
This gene plays a prominent role in tumor suppression. »
Encoded by human ANP32D Gene, 131-amino acid 14.8 kD PP32R2 Protein (PP32 Family) shares approximately 90% amino acid sequence identity with tumor… »
Human ANP32D wild-type allele is located in the vicinity of 12q13.11 and is less than 1 kb long. This allele, which encodes… »
This gene plays a role in peptide hydrolysis. »
Human ANPEP wild-type allele is located within 15q25-q26 and is approximately 30 kb in length. This allele, which encodes aminopeptidase N protein,… »
A humanized monoclonal antibody directed against interleukin-13 (IL-13) with anti-asthmatic and anti-inflammatory activities. Anrukinzumab binds to and blocks the activity of IL-13,… »
The part of the nervous system that controls muscles of internal organs (such as the heart, blood vessels, lungs, stomach, and intestines)… »
Medicamento contra el cáncer que es un tipo de antibiótico antineoplásico. »
An ansamacrolide and maytansine analogue originally isolated from the Ethiopian shrub Maytenus serrata with antineoplastic activity. Ansamitomicin P-3 binds to tubulin at… »
An anticancer drug that belongs to the family of drugs called antineoplastic antibiotics. »
An antineoplastic antibiotic of macrocyclic benzoquinone isolated from the bacterial genus Streptomyces. Ansamycin antibiotics bind to and inhibit the cytosolic chaperone functions… »
Deseo fuerte, urgente o anormal de una sustancia o actividad. Hay diferentes tipos de ansias o antojos, como los antojos de comida… »
Sentimientos de miedo, pavor e incomodidad que podrían presentarse como consecuencia de un estado de tensión. Una persona con ansiedad, podría sudar,… »
Grado de sedación en el que una persona está muy relajada y puede estar despierta. La persona puede responder preguntas y cumplir… »
Medicamento que se usa para tratar los síntomas de ansiedad, como los sentimientos de temor, terror, incomodidad y tensión muscular, que se… »
A statement (either spoken or written) that is made in reply to a question or request or criticism or accusation; a statement… »
An electronic device that answers a telephone and records messages. »
Natural or synthetic compounds or mixtures, Antiacid Preparations such as sodium bicarbonate, sodium citrate, and phosphate salts act as proton acceptors, neutralizing… »
In medicine, a substance that stops the action or effect of another substance. For example, a drug that blocks the stimulating effect… »
En el campo de la medicina, sustancia que frena la acción o el efecto de otra sustancia. Por ejemplo, un medicamento que… »
Sustancia que relaja tejido muscular en los vasos sanguíneos y en la próstata, lo que mejora el flujo de la orina y… »
Sustancia que impide que la hipófisis elabore hormonas que se llaman hormona estimulante de los folículos (FSH) y hormona luteinizante… »
Sustancia que impide que la hipófisis elabore hormonas que se llaman hormona estimulante de los folículos (FSH) y hormona luteinizante… »
Sustancia que impide que la hipófisis elabore hormonas que se llaman hormona estimulante de los folículos (FSH) y hormona luteinizante… »
Sustancia que impide que la hipófisis elabore hormonas que se llaman hormona estimulante de los folículos (FSH) y hormona luteinizante… »
Tipo de medicamento que impide que las células usen ácido fólico para elaborar ADN y podría destruir células cancerosas. Ciertos antagonistas del… »
Tipo de medicamento que impide que las células usen ácido fólico para elaborar ADN y podría destruir células cancerosas. Ciertos antagonistas del… »
Tipo de medicamento que se usa para tratar ciertos tipos de síndrome del colon irritable, y aliviar náuseas y vómitos. Es un… »
Tipo de medicamento que se usa para tratar ciertos tipos de síndrome del colon irritable, y aliviar náuseas y vómitos. Es un… »
Medicamento que bloquea la hormona endotelina y podría prevenir que el cáncer de próstata se disemine hacia los huesos. También podría prevenir… »
Sustancia que impide la unión de la proteína endotelina-1 con su receptor. La endotelina-1 es una molécula pequeña que produce cambios en… »
Tipo de medicamento que se usa para tratar ciertos tipos de síndrome del colon irritable, y aliviar náuseas y vómitos. Es un… »
An ethylenediamine derivative with histamine H1 antagonistic and sedative properties. Antazoline antagonizes histamine H1 receptor and prevents the typical allergic symptoms caused… »
The phosphate salt of antazoline, an ethylenediamine derivative with histamine H1 antagonistic and sedative properties. Antazoline antagonizes histamine H1 receptor and prevents… »
Registro de las relaciones entre los miembros de una familia junto con sus antecedentes médicos. Los antecedentes familiares pueden mostrar las características… »
Registro con información sobre la salud de una persona. Los antecedentes médicos personales pueden incluir información acerca de las alergias,… »
Registro de las relaciones entre los miembros de una familia junto con sus antecedentes médicos. Los antecedentes médicos familiares pueden mostrar las… »
Recopilación de información acerca de la salud de una persona. Puede incluir información sobre alergias, enfermedades y cirugías; fechas y… »
Recopilación de información acerca de la salud de una persona. Puede incluir información sobre alergias, enfermedades y cirugías; fechas y… »
A triangular space on the anterior side of the elbow joint. Three main veins of the arm, the brachial artery, the medial… »
The area of the body that is anterior to the elbow. »
Having to do with the time a female is pregnant, before birth occurs. Also called prenatal. »
Relacionado con el período en que una hembra está embarazada, antes del nacimiento. También se llama prenatal. »
A device designed to transmit or receive electromagnetic signals. »
Los anteojos protegen la vista o la corrigen. Algunos ejemplos son los anteojos de sol, las gafas de seguridad, los anteojos y… »
The period of time preceding labor and delivery. »
Presence of a large air bubble in the maternal vascular system which originated from a distant site during the antepartum period. … »
Presence of bacterially-infected tissue in the maternal vascular system which originated from a distant site during the antepartum period. »
Presence of a blood clot in the maternal vascular system which originated from a distant site during the antepartum period. »
Fetal death greater than or equal to 20 weeks of gestation prior to labor and Apgar scores of 0 at 1 minute,… »
In human anatomy, has to do with the front of a structure, or a structure found toward the front of the… »
En el campo de la anatomía humana, se relaciona con el frente de una estructura o con una estructura que se encuentra… »
A muscle located in the anterior aspect of the abdominal wall. »
A ligament present in the wrist and the ankle. In the wrist it is located over the carpus and in the ankle… »
A vein that drains the auricle and acoustic meatus of the external ear. »
A vein that drains blood from the cranium into the common cardinal vein during embryonic development. »
One of the arteries that deliver blood to the wrist. It arises from the radial artery and forms an anastomosis with the… »
A vein that it is part of the deep intracranial venous system. »
One of the two arteries arising from the internal carotid artery and being part of the Circle of Willis. Both left and… »
An arterial branch arising from the anterior cerebral artery. It includes the callosomarginal artery, frontopolar artery, medial orbitofrontal artery, pericallosal artery, and… »
The space in the eye, filled with aqueous humor, bounded anteriorly by the cornea and a small portion of the sclera and… »
An artery, which originates in either the internal carotid artery or the middle cerebral artery, that delivers blood to the choroid… »
An axillary artery branch with distribution to the humeral head and biceps muscle. »
A rounded band or bundle of nerve fibers that connects the two hemispheres of the brain. »
An artery that joins the two anterior cerebral arteries. »
The internal area of the skull that holds the frontal lobes. »
A meningioma that affects the anterior cranial fossa. »
A major stabilizing ligament in the knee that attaches the surfaces of the femur and tibia. »
A left coronary artery branch that descends on the anterior portion of the heart through the anterior interventricular groove. »
The part of the eye anterior to the lens, including but not limited to the anterior chamber, cornea and related structures. … »
A vein that represents a continuation of the angular vein and lies behind the facial artery. »
The anterior aspect of the foramen magnum formed by the basilar part of the occipital bone. »
A meningioma that affects the anterior foramen magnum. »
Anterior gradient protein 2 homolog (175 aa, ~20 kDa) is encoded by the human AGR2 gene. This protein is involved in the… »
Motor neurons in the anterior (ventral) horn of the spinal cord which project to skeletal muscles. »
A basilar artery branch that supplies the anterior portion of the inferior surface of the cerebellum. »
The orbital part of the inferior frontal convolution. »
An anterior infratentorial subarachnoid cistern. »
A vein arising near the hyoid bone from several veins from the submaxillary region. It terminates in the external jugular vein. … »
The glandular or anterior lobe of the pituitary gland which secretes several hormones. »
A ligament running the length of the anterior surface of the spinal column and thereby interconnects all the vertebral bodies. »
A fissure in the midline of the anterior surface of the spinal cord. »
A lymph node located in the superior mediastinum that collects lymph from the thymus, the pericardium, and the right side of the… »
A procedure in which a tube is inserted into the chest to view the tissues and organs in the area between the… »
The area in the front part of the chest between the lungs. Also called prevascular space. »
An anterior ethmoidal artery branch that supplies the meningeal tissues in the anterior fossa of the cranium. »
An electrocardiographic finding of pathologic Q waves in leads V3 and V4, which is suggestive of myocardial infarction of the anterior wall… »
A fetal position during delivery in which the head of the fetus faces the mother's back. »
An experimental concept that relates to the anterior region of the olfactory bulb. »
A nucleus that is located in the olfactory tract. »
The artery that delivers blood to the anterior portion of the parietal lobe. »
The anterior portion of a deep fissure or furrow on the medial surface of the cerebral cortex. »
Surgery to remove the urethra, lower part of the ureters, uterus, cervix, vagina, and bladder. »
A functioning or non-functioning endocrine neoplasm that arises from the anterior lobe of the pituitary gland. It is classified either as… »
A neoplasm arising from the anterior lobe of the pituitary gland. The vast majority are adenomas. »
The central area in the anterior surface of the lens. »
The frontal aspect of the cistern of the corpus callosum. »
The portion of the urethra that extends from the meatus to the membranous urethra. »
The anterior eminence of the lamina tecti mesencephali. »
The artery that delivers blood to the anterior portion of the spinal cord. »
One of the supratentorial cisterns. It is also called parasellar supratentorial cistern. »
The lingual or upper surface of the epiglottis. »
The aspect of the kidney facing the abdominal cavity. »
The anterior surface of the lens of the eye. »
The anterior surface of the liver tissue. It consists of the right and left lobes. »
The aspect of the prostate facing the pubic symphysis. »
The anterior aspect of the stomach. »
The surface of the vagina that is in relation with the bladder and the urethra. »
A branch of the middle cerebral artery that supplies blood to the anterior part of the temporal lobe. »
An artery of the lower extremity that supplies blood to the anterior part of the leg and the foot. »
An arterial branch arising from the anterior tibial artery. »
The vein that runs parallel to the anterior tibial artery and empties into the popliteal vein. »
An adenoid cystic carcinoma arising from the minor salivary glands in the anterior tongue. »
A carcinoma that arises from the anterior two-thirds of the tongue. Representative examples include squamous cell carcinoma, adenoid cystic carcinoma, and… »
A mucoepidermoid carcinoma arising from the minor salivary glands in the anterior tongue. »
A benign or malignant neoplasm that affects the anterior portion of the tongue. »
A squamous cell carcinoma that arises from the anterior two-thirds of the tongue. It usually presents as a painful ulcerated or… »
The anterior border of the tonsillar fossa. It is composed of the palatoglossus muscle. »
A vein that extends along the ulna to the elbow joint. »
A disease in which malignant (cancer) cells are found in the part of the urethra (the tube through which urine leaves the… »
A malignant neoplasm that affects the portion of the urethra that is close to the outside of the body. »
Inflammation of the anterior uvea comprising the iris, angle structures, and the ciliary body. Manifestations of this disorder include ciliary injection, exudation… »
One of the neural pathways that transmit impulses from the eyes to the cerebral cortex. »
A meningioma that affects the anterior visual pathway. »
The anterior aspect of the bladder wall. »
The anterior aspect of the nasopharynx. »
The anterior aspect of the tympanum. »
The nervous tract that carries pain, temperature, and tactile signals from the periphery to the brain. »
The lateral white column of the spinal cord between the lines of exit and entrance of the anterior and posterior nerve… »
Denoting the area of the body in front and away from the middle line. »
An electrocardiographic finding of pathologic Q waves in leads V3 through V6, which is suggestive of myocardial infarction of the anterolateral wall… »
Directed from front to back. »
An electrocardiographic finding of pathologic Q waves in leads V1 through V4, which is suggestive of myocardial infarction of the anteroseptal wall… »
The pollen bearing portion of a stamen. »
A flavonoid with a positively charged oxygen in the pyran moiety that has 5 double bonds in the benzopyran group. »
A flavonoid that is a glycoside derivative of anthocyanidin. They are water-soluble plant pigments that exhibit bright coloration. Their color is dependent… »
A naturally occurring, rare, fibrous amphibole asbestos mineral with a color ranging from grayish-white to green. Chronic inhalation of its dust may… »
Anthracene, also called paranaphthalene or green oil, a solid polycyclic aromatic hydrocarbon (PAH) consisting of three benzene rings derived from coal-tar, is… »
An anticancer drug that belongs to the family of drugs called anticancer antibiotics. »
A mixed condition of anthracosis and silicosis. (Dorland, 27th ed) »
A chronic lung disorder characterized by deposition of coal dust in the lung parenchyma leading to the formation of black nodules and… »
A type of antibiotic that comes from certain types of Streptomyces bacteria. Anthracyclines are used to treat many types of cancer. Anthracyclines… »
A synthetic non-cardiotoxic analogue of the anthracycline antibiotic doxorubicin with potential antineoplastic activity. Anthracycline analogue GPX-150 intercalates DNA and impedes the activity… »
An antineoplastic antibiotic that is structurally similar to the benzoquinone ansamycin antibiotic geldanamycin. A geldanamycin analogue binds to HSP90, a chaperone protein… »
A natural anthraquinone derivative, anti-psoriatic and anti-inflammatory Anthralin (dithranol) controls skin growth by reducing DNA synthesis and mitotic activity in the hyperplastic… »
A pyrrolo(1,4)benzodiazepine antineoplastic antibiotic isolated from the bacterium Streptomyces refuineus var. thermotolerans. Anthramycin binds covalently to guanine in the minor groove… »
An antineoplastic antibiotic that intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein… »
A class of antibiotics related to the anthracycline antineoplastic antibiotics. The anthrapyrazole antibiotics intercalate into DNA and interact with topoisomerase II,… »
A type of anticancer drug. »
A substance that is based on the structure of anthraquinone and inhibits topoisomerase-II by intercalating into the DNA double strand. »
An infection caused by Bacillus anthracis bacteria. It may affect the lungs, gastrointestinal tract, or skin. Patients with lung infection present with… »
One of the key causes of anthrax virulence is the action of three specific factors produced by the bacterium Bacillus anthracis. Even… »
Anthrax toxin receptor 1 (564 aa, ~63 kDa) is encoded by the human ANTXR1 gene. This protein plays a role in the… »
Generated by the actions of humans. »
The branch of science concerned with origin and development of humans in all their physical, social, and cultural relationships. »
An antibody-drug conjugate composed of an antibody directed against 5T4 and conjugated, via the stable linker maleimidocaproyl (mc), to the microtubule inhibitor… »
A recombinant fully human monoclonal antibody directed against the human A33 antigen, with potential immunomodulatory and antineoplastic activity. Anti-A33 monoclonal antibody KRN330… »
A monoclonal antibody directed against the human alpha5beta1 integrin with potential antiangiogenic and antineoplastic activities. Anti-alpha5beta1 integrin monoclonal antibody PF-04605412 selectively binds… »
An agent that inhibits metastasis by interfering with the binding of tumor cells to each other or to endothelial cells. »
Substances that inhibit the biologic effects of the adrenal hormones by interfering with their synthesis, metabolism, or binding to their receptor… »
A humanized monoclonal antibody directed against the activator of g-proteins signaling (AGS) cell surface protein AGS-16 with potential antineoplastic activity. Anti-AGS-16 monoclonal… »
An antibody drug conjugate (ADC) containing the fully human IgG2k monoclonal antibody targeting an epitope of SLC44A4 (AGS-5) linked, via a valine-citrulline… »
A humanized monoclonal antibody directed against the activator of g-proteins signaling (AGS) cell surface protein AGS-8 with potential antineoplastic activity. Anti-AGS-8 monoclonal… »
A fully human, IgG2 monoclonal antibody directed against activin-like receptor kinase 1 (ALK-1) with potential antineoplastic activity. Anti-ALK-1 monoclonal antibody PF-03446962 binds… »
A humanized monoclonal antibody directed against the human alpha v integrin subunit with potential antiangiogenic and antineoplastic activities. Anti-human integrin alpha v… »
A monoclonal antibody against amyloid with potential use in the treatment of amyloid light chain (AL) and AA amyloidosis. Upon intravenous administration,… »
Substances that inhibit or antagonize the biosynthesis or biologic effects of androgens by either antagonizing the responsiveness of androgen sensitive tissues or… »
A fully human IgG1 monoclonal antibody against angiopoietin 2 (ANG2), with potential antiangiogenic activity. Anti-ANG2 monoclonal antibody MEDI-3617 binds to Ang2 and… »
Classified as bronchodilators (beta-adrenoreceptor agonists, xanthines, muscarinic-receptor antagonists) and anti-inflammatory agents (glucocorticoids, cromolyn), natural or synthetic Anti-asthmatic Agents relieve asthma (a recurrent… »
An immunotoxin comprised of an anti-B4 (anti-CD19) murine monoclonal antibody linked to the modified plant-derived toxin blocked ricin. The antibody moiety of… »
A monoclonal antibody directed against B7H1 (B7 homolog 1; programmed cell death ligand 1) with potential immunostimulating activity. Upon intravenous administration, MEDI4736… »
A fully human IgG2 monoclonal antibody against the colony-stimulating factor-1 (CSF-1 or M-CSF) receptor c-fms (or CSFR1), with potential antineoplastic activity. Upon… »
A monoclonal antibody directed against human hepatocyte growth factor receptor (HGFR or c-Met), with potential antineoplastic activity. Anti-c-Met monoclonal antibody ABT-700 binds… »
A humanized IgG4 monoclonal antibody directed against human hepatocyte growth factor receptor (HGFR or c-MET) with potential antineoplastic activity. Anti-c-MET monoclonal antibody… »
An immunoconjugate consisting of a humanized monoclonal antibody against the tumor-associated sialoglycotope CA6 (huDS6) conjugated to the cytotoxic maytansinoid DM4, with potential… »
A substance being studied as a treatment for atherosclerosis (a build-up of fat in the arteries). It is also being studied in… »
A chimeric IgG1 monoclonal antibody against CD123 (Interleukin-3 receptor alpha chain) with potential antineoplastic activity. Derived from mouse monoclonal antibody 7G3, anti-CD123… »
A humanized IgG1 monoclonal antibody against CD123 (Interleukin-3 receptor alpha chain or IL3RA) with potential antineoplastic activity. Upon intravenous administration, anti-CD123 monoclonal… »
An immunoconjugate consisting of an anti-CD19 monoclonal antibody conjugated to the auristatin derivative monomethyl auristatin F (MMAF), with potential antineoplastic activity. Upon… »
A monoclonal antibody linked to a toxic substance. It is being studied in the treatment of some types of B-cell cancer. Anti-CD19… »
A class of immunotoxins targeting CD19, a common B-cell marker. »
Any monoclonal antibody directed against the cell surface glycoprotein CD19, regardless of the antibody type. »
A low-fucosylated, humanized, IgG1 isotype, monoclonal antibody directed against the B-cell-specific membrane protein CD19 with potential immunostimulating and antineoplastic activities. Anti-CD19 monoclonal… »
A fully human anti-CD19 monoclonal antibody directed against the B-cell-specific membrane protein CD-19 with potential antineoplastic activity. Anti-CD19 monoclonal antibody MDX-1342 binds… »
A humanized immunoglobulin IgG1 kappa monoclonal antibody directed against the B-cell-specific membrane protein CD-19 with potential immunostimulating and antineoplastic activities. Anti-CD19 monoclonal… »
An Fc engineered, humanized anti-CD19 monoclonal antibody directed against the B-cell-specific membrane protein CD19 with potential immunostimulating and antineoplastic activities. Anti-CD19 monoclonal… »
Allogeneic T-lymphocytes derived from peripheral blood mononuclear cells (PBMC) transduced with a retroviral vector expressing a chimeric antigen receptor (CAR) consisting of… »
A preparation of autologous peripheral blood T-lymphocytes (PBTL) that have been genetically modified to express a chimeric antigen receptor (CAR) consisting of… »
Allogeneic natural killer (NK) cells transduced with an mRNA expressing a chimeric antigen receptor (CAR) consisting of an anti-CD19 scFv (single chain… »
An immunoconjugate consisting of an anti-CD19 monoclonal antibody conjugated to the maytansinoid DM4, a derivative of the cytotoxic agent maytansine (DM1), with… »
An immunotoxin consisting of two scFv ligands recognizing human CD19 and CD22 linked to the first 389 amino acids of diphtheria toxin… »
Any monoclonal antibody directed against the cell surface glycoprotein CD2, regardless of the antibody type. »
A third-generation, humanized monoclonal antibody directed against human CD20 with potential antineoplastic activity. Anti-CD20 monoclonal antibody PRO131921 specifically binds to the B… »
A monoclonal antibody directed against human CD20 with potential antineoplastic activity. Anti-CD20 monoclonal antibody TL011 specifically binds to the B cell-specific cell… »
A preparation of autologous blood T-lymphocytes that have been genetically modified to express a chimeric antigen receptor (CAR) consisting of an anti-CD20… »
A humanized monoclonal antibody directed against the human immunosuppressive molecule CD200 (OX-2) with potential immunomodulating and antineoplastic activities. Anti-CD200 monoclonal antibody ALXN6000… »
A monoclonal antibody linked to a toxic substance. It is being studied in the treatment of some types of B-cell cancer. Anti-CD22… »
A monoclonal antibody linked to a toxic substance. It is being studied in the treatment of some types of B-cell cancer. Anti-CD22… »
An antibody-drug conjugate (ADC) composed of MCDT2219A , a humanized IgG1 anti-CD22 monoclonal antibody covalently linked, via a protease-cleavable peptide linker, to… »
Any monoclonal antibody directed against the alpha subunit of the human interleukin 2 receptor. »
A human agonistic monoclonal antibody (MoAb) specific for CD27, with potential immunostimulating and antineoplastic activity. Upon administration of CDX-1127, this MoAb binds… »
An immunoconjugate consisting of a human IgG1 monoclonal antibody directed against CD27L conjugated, via a non-cleavable linker, to the cytotoxic agent maytansinoid… »
A bivalent recombinant fusion protein immunotoxin derived from the anti-CD3 monoclonal antibody UCHT1 with potential antineoplastic activity. Anti-CD3 immunotoxin A-dmDT390-bisFv(UCHT1) consists of… »
Any monoclonal antibody directed against the cell surface glycoprotein CD3, regardless of the antibody type. »
Autologous activated T cells that have been coated with bispecific antibodies (BiAb), with potential antineoplastic and immunomodulating activities. In vitro, T cells… »
A trifunctional bispecific monoclonal antibody with potential antineoplastic activity. FBTA05 contains two antigen-recognition sites: one for human CD3, a T cell surface… »
A fully human, second-generation, nonfucosylated monoclonal antibody directed against the cell surface receptor CD30 with potential immunomodulating and antineoplastic activities. Anti-CD30 monoclonal… »
A humanized monoclonal antibody directed against the cell surface receptor CD30 with potential immunotherapeutic activity. Anti-CD30 monoclonal antibody XmAb2513 specifically binds to… »
A tetravalent bispecific antibody directed against human CD30 and the human low affinity IgG Fc region receptor (FCGR3A; CD16A), with potential immunomodulating… »
An immunoconjugate consisting of a humanized monoclonal antibody that is engineered to contain cysteine residues that are conjugated to the synthetic, DNA… »
An immunoconjugate of the humanized monoclonal antibody hP67.6 chemically linked to a bacterial toxin, N-acetyl-gamma calicheamicin, by 4-acetylphenylacetic acid, with antileukemic… »
An immunoconjugate consisting of the humanized monoclonal antibody huMy9-6 conjugated to the cytotoxic maytansinoid DM4 with potential antineoplastic activity. The monoclonal antibody… »
An immunoconjugate that consists of a humanized IgG1 antibody K7153A against the cell-surface antigen CD37 and covalently linked via the uncleavable, maleimide-derived… »
A fully human monoclonal antibody directed against the cell surface glycoprotein CD-38 with potential antineoplastic activity. Anti-CD38 monoclonal antibody MOR03087 specifically binds… »
A humanized IgG1 monoclonal antibody directed against the cell surface glycoprotein CD-38 with potential antineoplastic activity. Anti-CD38 monoclonal antibody SAR650984 specifically binds… »
Any monoclonal antibody directed against the cell surface glycoprotein CD4, regardless of the antibody type. »
An IgG1 chimeric monoclonal antibody agonist of the cell surface receptor CD40 with potential immunostimulatory and antineoplastic activities. Upon intravenous administration, anti-CD40… »
An immunoconjugate containing a monoclonal antibody directed against the CD45 antigen BC8, conjugated to streptavidin, a nonglycosylated homotetrameric protein that has four… »
A monoclonal antibody being studied in the treatment of some types of cancer. Monoclonal antibodies are made in the laboratory and can… »
A high affinity IgG1 monoclonal antibody with potential immunotherapeutic activity. Anti-CD45 monoclonal antibody AHN-12 recognizes CD45, a transmembrane protein tyrosine phosphatase that… »
A murine IgG1 anti-CD45 monoclonal antibody (MoAb) with immunotherapeutic activity. CD45 antigen, a receptor protein-tyrosine phosphatase essential for T cell development and… »
Any monoclonal antibody directed against the cell surface glycoprotein CD5, regardless of the antibody type. »
Any monoclonal antibody directed against the cell surface glycoprotein CD52, regardless of the antibody type (e.g., rat, mouse, humanized). »
Any monoclonal antibody directed against the cell surface glycoprotein CD6, regardless of the antibody type. »
A toxin linked to an anti-CD7 antibody. »
Any monoclonal antibody directed against the cell surface glycoprotein CD7, regardless of the antibody type. »
An antibody-drug conjugate (ADC) containing a fully human monoclonal antibody, directed against the extracellular domain of the human CD70 molecule, conjugated to… »
A defucosylated, humanized IgG1 monoclonal antibody directed against the extracellular domain of the human CD70 molecule with potential antineoplastic activity. Upon administration,… »
A glycoengineered, fully humanized IgG1 monoclonal antibody directed against the extracellular domain of the human CD70 molecule with potential antineoplastic activity. Anti-CD70… »
An antibody-drug conjugate (ADC) composed of a monoclonal antibody directed against B-cell antigen receptor complex-associated protein beta chain (CD79B) conjugated, via a… »
Any monoclonal antibody directed against the cell surface glycoprotein CD8, regardless of the antibody type. »
An antibody against carcinoembryonic antigen (CEA), a protein present on certain types of cancer cells. »
A recombinant, proprietary bispecific T-cell engagers (BiTE) antibody directed against human carcinoembryonic antigen (CEA), with potential immunostimulating and antineoplastic activities. Anti-CEA BiTE… »
A population of autologous tumor infiltrating lymphocytes (TIL) transduced with a retroviral vector encoding the chimeric gene IgCD28TCR with potential immunostimulating and… »
Autologous human peripheral blood lymphocytes (PBLs), transduced with a retroviral vector encoding both the alpha and beta chains of a T cell… »
A bispecific monoclonal antibody (BsMAb) consisting of the Fab fragment of an anti-CEA monoclonal antibody (F6) coupled to the Fab fragment of… »
A tri-Fab bispecific monoclonal antibody (BiMoAb) divalent for the carcinoembryonic antigen (CEA) and monovalent for histamine-succinyl-glycine (HSG) peptide-hapten. Anti-CEA/anti-HSG bispecific monoclonal antibody… »
A unit of anti-coagulation factor potency determined using an in vitro clotting assay against the standard for coagulation factor concentrate. »
A unit of anti-factor Xa anticoagulation activity of unfractionated or low molecular weight heparin. »
A monoclonal antibody directed against colony stimulating factor 1 receptor (CSF1R) with potential antineoplastic activity. CSF1R monoclonal antibody IMC-CS4 binds to CSF1R… »
A human monoclonal antibody targeting connective tissue growth factor (CTGF) with potential anti-fibrotic and antineoplastic activities. FG-3019 binds to CTGF thereby preventing… »
An autologous dendritic cell (DC) cancer vaccine with potential immunostimulatory activity. Anti-CTLA4 MoAb RNA-transfected autologous DC vaccine is prepared by transfecting DCs… »
An autologous dendritic cell (DC) cancer vaccine with potential immunostimulatory activity. Anti-CTLA4 MoAb RNA/GITRL RNA-transfected DC vaccine is prepared by transfecting DCs… »
An orally bioavailable monoclonal antibody against CXC Chemokine Receptor 4 (CXCR4) with potential antineoplastic activity. CXCR4 monoclonal antibody MDX-1338 binds to the… »
Drug treatment to reduce the activity of cytokines, particulary to control inflammation in disease modalities. »
A humanized, affinity-matured IgG1k antibody directed against denatured collagens (I-IV) with potential antiangiogenic and antineoplastic activities. Anti-denatured collagen recombinant monoclonal antibody TRC093… »
Any substance used to reduce hyperglycemia or treat disorders associated with diabetes. Based on their mechanism of action, this class of agents… »
A human monoclonal antibody directed against the WNT antagonist dickkopf homolog 1 (DKK1), with potential anti-osteolytic activity. Anti-DKK1 monoclonal antibody LY2812176 binds… »
A humanized monoclonal antibody directed against Wnt antagonist Dickkopf-1 (DKK1) with potential anti-osteolytic activity. Anti-DKK1 monoclonal antibody BHQ880 binds to and inhibits… »
An immunoglobulin G1 lambda monoclonal antibody directed against the Notch ligand delta-like 4 (DLL4) with potential antineoplastic activity. Anti-DLL4 monoclonal antibody MEDI0639… »
A human monoclonal antibody directed against Delta-like ligand-4 (DLL4) with potential antineoplastic activity. Anti-DLL4 monoclonal antibody REGN421 specifically binds to human… »
An antinuclear autoantibody directed against nuclear DNA. »
The determination of the amount of anti-DNA antibodies present in a sample. »
An immunoconjugate of the anti-dopamine-b-hydroxylase monoclonal antibody covalently linked to the ribosome-inactivating protein (RIP) saporin derived from Saponaria officinalis. The monoclonal antibody… »
The determination of the amount of anti-double stranded DNA present in a sample. »
An agonist mouse monoclonal antibody directed against TRAIL death receptor type 5 (DR5) with potential antineoplastic activity. Anti-DR5 agonist monoclonal antibody TRA-8… »
An antibody that binds to an administered drug. Expression of these antibodies is thought to be induced by (repeated) drug administration. … »
A humanized IgG1 monoclonal antibody directed against the epidermal growth factor-like domain multiple 7 (EGFL7) with potential antineoplastic activity. Anti-EGFL7 monoclonal antibody… »
A humanized monoclonal antibody (MoAb) against human epidermal growth factor receptor (EGFR) with antineoplastic activity. MoAb ABT-806 targets the EGFR deletion variant,… »
A glycoengineered form of a human monoclonal antibody directed against the epidermal growth factor receptor (EGFR) with potential antineoplastic activity. Anti-EGFR monoclonal… »
An oligoclonal therapeutic composed of three fully human monoclonal antibodies targeting epidermal growth factor receptor (EGFR or ErbB1), with potential antineoplastic… »
A mixture of two recombinant IgG1 antibodies directed against different epitopes in the epidermal growth factor receptor (EGFR) extracellular domain III, with… »
A glycoengineered monoclonal antibody directed against the epidermal growth factor receptor (EGFR) with potential antineoplastic activity. Anti-EGFR monoclonal antibody RO5083945 binds to… »
A targeted antibody payload (TAP)-based immunoconjugate consisting of a human monoclonal antibody directed against the epidermal growth factor receptor (EGFR) conjugated, via… »
An immunoconjugate consisting of a human monoclonal antibody directed against the deletion-mutant of epidermal growth factor receptor, EGFRvIII, conjugated via a non-cleavable… »
Allogeneic human T-lymphocytes transduced with a retroviral vector encoding an anti-epidermal growth factor receptor (EGFR) variant III (EGFRvIII) mutant chimeric T cell… »
A recombinant immunotoxin consisting of single-chain variable domain fragment antibody directed against the tumor-specific antigen EGFRvIII (MR1scFv) fused to domains II and… »
An immunotoxin consisting of a monoclonal antibody directed against epithelial glycoprotein-2 (EP-2, or epithelial cell adhesion molecule (EpCAM)) conjugated to the bacterial… »
A human/murine chimeric monoclonal antibody directed against endoglin (CD105) with potential antiangiogenic and antineoplastic activities. Anti-endoglin monoclonal antibody TRC105 binds to endoglin,… »
Monoclonal antibody K4-2C10 conjugated with deglycosylated ricin A chain. This antibody recognizes human endoglin (Transforming Growth Factor P Receptor III), present… »
A humanized IgG1 monoclonal antibody directed against human endosialin/TEM1 (tumor endothelial marker;CD248) with potential anti-angiogenic and antineoplastic activities. Anti-endosialin/TEM1 monoclonal antibody MORAb-004… »
An antibody-drug conjugate (ADC) containing a fully human monoclonal antibody (AGS-16C) directed to the ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (ENPP3), conjugated via… »
A fusion protein immunotoxin consisting of a humanized, single-chain monoclonal antibody fragment specific for the epithelial cell adhesion molecule (EpCAM) conjugated with… »
A substance being studied in the treatment of certain types of head and neck cancer. Anti-EpCAM-Pseudomonas-exotoxin fusion protein is made by linking… »
Sustancia en estudio para el tratamiento de ciertos cánceres de cabeza y cuello. La anti-EpCAM-Pseudomonas-proteína de fusión de exotoxina se elabora uniendo… »
An auristatin analogue immunoconjugate directed against Eph receptor A2 (EphA2)-positive cancer cells with potential antineoplastic activity. Anti-EphA2 monoclonal antibody-MMAF immunoconjugate MEDI-547 is… »
A bispecific monoclonal antibody directed against the human epidermal growth factor receptors ErbB2 (Her2) and ErbB3 (Her3) with potential antineoplastic activity. The… »
A humanized monoclonal antibody (MoAb) directed against the human receptor tyrosine-protein kinase ErbB-3 (HER3) with potential antineoplastic activity. Anti-ErbB3 MoAb AV-203 binds… »
A monoclonal antibody directed against the human epidermal growth factor receptor ErbB3 (Her3) with potential antineoplastic activity. Anti-ErbB3 monoclonal antibody KTN3379 binds… »
A human monoclonal antibody directed against the human epidermal growth factor receptor ErbB3 (Her3) with potential antineoplastic activity. Anti-ErbB3 receptor monoclonal antibody… »
A fully human monoclonal antibody directed against the human epidermal growth factor receptor ErbB3 (Her3) with potential antineoplastic activity. Anti-ErbB3 receptor monoclonal… »
A bispecific monoclonal antibody directed against the human epidermal growth factor receptor ErbB3 (Her3) and the human insulin-like growth factor-1 receptor (IGF-1R),… »
The determination of the amount of anti-activated Factor X present in a sample. This test is used to monitor low molecular weight… »
An antibody against the fibroblast growth factor receptor type 2 (FGFR2), with potential antineoplastic activity. Upon administration, the anti-FGFR2 antibody BAY1179470 binds… »
A fully human, IgG1 monoclonal antibody directed against the FLT3 tyrosine kinase receptor (CD135) with potential antineoplastic activity. Upon binding to FLT3,… »
An immunoconjugate consisting of the humanized monoclonal antibody M9346A against folate receptor 1 (FOLR1) conjugated, via the disulfide-containing cleavable linker sulfo-SPDB, to… »
A humanized anti-ganglioside GM2 (GM2) monoclonal antibody with potential antineoplastic and immunomodulating activities. Upon administration, anti-ganglioside GM2 monoclonal antibody BIW-8962 may activate… »
An antibody-drug conjugate (ADC) containing a monoclonal antibody directed against guanylyl cyclase C (GCC or GUCY2C) conjugated to monomethylauristatin E (MMAE), an… »
A monoclonal antibody directed against human glycosphingolipid GD2 with potential antineoplastic activity. Upon binding to the GD2 antigen, anti-GD2 monoclonal antibody hu14.18K322A… »
A human IgM monoclonal antibody directed against disialoganglioside GD2 with potential immunomodulating activity. Upon administration, anti-GD2 monoclonal antibody MORAb-028 may stimulate the… »
Natural or synthetic Anti-glaucoma Agents relieve or prevent glaucoma, a condition characterized by increased intraocular pressure, excavation, and optic nerve damage. Such… »
An autoimmune disorder characterized by the production of autoantibodies against type IV collagen of the glomerular basement membrane of the kidney. In… »
A peptide vaccine derived from the synthetic peptide pyroEHWSYGLRPG, corresponding to amino acids 22-31 of mouse gonadotropin releasing hormone (GnRH), with potential… »
Pharmaceutical Anti-gout Preparations such as colchicine, allopurinol, probenecid, and sulfinpyrazone contain natural or synthetic agents against gout, a condition characterized by increased… »
Human peripheral blood lymphocytes (PBL) isolated from a melanoma patient and were engineered to react with the melanoma antigen glycoprotein 100… »
Human tumor infiltrating lymphocytes (TIL) isolated from a melanoma patient and were engineered to react with the melanoma antigen glycoprotein 100… »
A humanized monoclonal antibody directed against the cell surface oncofetal protein glypican-3 (GPC3) with potential antineoplastic activity. Anti-GPC3 monoclonal antibody GC33 binds… »
A IgM monoclonal antibody (MoAb) against 78-kDa glucose-regulated protein (GRP78; also called BiP or HSPA5), with potential proapoptotic and antineoplastic activities. Upon… »
A proprietary fucose-free monoclonal antibody directed against human heparin-binding EGF-like growth factor (HBEGF) with potential antineoplastic activity. Anti-HB-EGF Monoclonal Antibody KHK2866 binds… »
A humanized monoclonal antibody directed against human heparin-binding EGF-like growth factor (HBEGF) with potential antineoplastic activity. Anti-HBEGF monoclonal antibody U3-1565 binds to… »
One international unit of antihemophilic activity is equivalent to the quantity of antihemophilic factor (Factor VIII) present in 1 mL of normal… »
Autologous human peripheral blood lymphocytes (PBLs) transduced with a retroviral vector encoding an anti-Her-2 (epidermal growth factor receptor 2) chimeric T cell… »
A monoclonal antibody directed against the human epidermal growth factor receptor 2 (HER2) with potential immunomodulating and antineoplastic activity. After binding to… »
A Fc-domain optimized IgG monoclonal antibody directed against the human epidermal growth factor receptor 2 (HER2) with potential immunomodulating and antineoplastic… »
Autologous human cytomegalovirus (CMV)-specific human cytotoxic T-lymphocytes (CTLs) transduced with a retroviral vector encoding a human anti-Her-2 (epidermal growth factor receptor 2)… »
A monoclonal antibody directed against the human epidermal growth factor receptor 3 (HER3; ERBB3) with potential antineoplastic activity. Anti-HER3 monoclonal antibody GSK2849330… »
A human monoclonal antibody directed against the human epidermal growth factor receptor HER3 (ErbB3) with potential antineoplastic activity. Anti-HER3 monoclonal antibody LJM716… »
A fully human monoclonal antibody directed against the membrane-bound receptor HER3 (ERBB3) with potential antineoplastic activity. Anti-HER3 monoclonal antibody U3-1287 binds to… »
A substance being studied in the treatment of cancer. It binds to a protein called hepatocyte growth factor (HGF), which may cause… »
A humanized monoclonal antibody directed against human hepatocyte growth factor (HGF) with potential antineoplastic activity. Anti-HGF monoclonal antibody TAK-701 binds to the… »
A synthetic antisense oligodeoxynucleotide (AS ODN) targeting hypoxia-inducible factor-1alpha (HIF-1alpha) with potential antineoplastic activity. Anti-HIF-1alpha LNA antisense oligonucleotide EZN-2968 hybridizes with HIF-1alpha… »
Any agent that prevents the human immunodeficiency virus (HIV) from reproducing. »
Treatment of human immunodeficiency virus (HIV) infections with medications that target the virus directly, limiting the ability of infected cells to produce… »
An enzyme immunoassay for the qualitative detection of antibodies to human immunodeficiency viruses in human serum or plasma. »
A humanized IgG4 monoclonal antibody that targets the human leukocyte antigen HLA-DR, with potential antineoplastic activity. Upon administration, anti-HLA-DR monoclonal antibody IMMU-114… »
A peptide vaccine consisting of the whole or partial beta subunit of human chorionic gonadotrophin hormone (hCG), linked to an adjuvant carrier… »
A humanized, Fc disabled anti-human glucocorticoid-induced tumor necrosis factor receptor (GITR) monoclonal antibody (MoAb) with immunomodulating activity. Anti-human GITR MoAb TRX518 blocks… »
A procedure to isolate one or more anti-globulin antibodies from either serum derived from animals immunized with human serum globulins or from… »
A fully human IgG1 monoclonal antibody directed against intercellular adhesion molecule-1 (ICAM-1 or CD54), with potential antineoplastic activity. Anti-ICAM-1 monoclonal antibody BI-505… »
An antibody directed against the individual antigenic determinants (idiotopes) on the variable region of an immunoglobulin molecule. In principle an anti-idiotype… »
A monoclonal antibody that functionally mimics MUC-1 antigen, a tumor cell surface antigen. Administration of anti-idiotype MUC-1 monoclonal antibody may elicit… »
A synthetic antibody produced by a genetically homogenous population of hybrid cells (hybridoma) against determinant idiotypes (Id) which usually mimic human… »
A vaccine made of antibodies that see other antibodies as the antigen and bind to it. Anti-idiotype vaccines can stimulate the body… »
A murine anti-idiotypic monoclonal antibody (anti-Id MoAb) that is directed against an idiotype mimicking a disialoganglioside GD3. GD3 represents a major surface… »
A humanized monoclonal antibody directed against the human insulin-like growth factor-1 receptor (IGF-1R/CD221) with potential antineoplastic activity. Anti-IGF-1R monoclonal antibody AVE1642 specifically… »
A recombinant, fully human monoclonal antibody directed against the insulin-like growth factor-1 receptor (IGF-1R) with potential antineoplastic activity. Anti-IGF-1R human monoclonal antibody… »
A recombinant, human monoclonal antibody directed against the insulin-like growth factor 1 receptor (IGF-1R) with potential antineoplastic activity. Anti-IGF-1R recombinant monoclonal antibody… »
A humanized monoclonal antibody directed against insulin-like growth factors 1 and 2 (IGF-1/2) with potential antineoplastic activity. Anti-IGF1/2 monoclonal antibody MEDI-573 inhibits… »
Sustancia en estudio para el tratamiento de muchos tipos de cánceres. El anti-IGF1R anticuerpo monoclonal recombinado MK-0646 se adhiere a una proteína… »
A substance being studied in the treatment of many types of cancer. Anti-IGF1R recombinant monoclonal antibody MK-0646 binds to a protein called… »
A "true human" (cloned from human B lymphocytes) monoclonal antibody directed against interleukin-1 alpha (IL1a) with potential antineoplastic activity. Anti-IL-1 alpha monoclonal… »
A human IgG1 monoclonal antibody directed against interleukin-1 alpha (IL1a) with potential antineoplastic activity. Anti-IL-1 alpha monoclonal antibody MABp1 binds to IL1a… »
A humanized monoclonal antibody directed against interleukin-13 (IL-13) with potential antineoplastic activity. Anti-IL-13 humanized monoclonal antibody TNX-650 binds to and blocks the… »
A chimeric (made from human and mouse proteins) monoclonal antibody being studied in the treatment of advanced kidney cancer and other types… »
Substances that prevent infectious agents or organisms from spreading or kill infectious agents in order to prevent the spread of infection. … »
For internal or topical application, Anti-infective Preparations contain natural or synthetic antibiotic agents that act therapeutically or prophylactically against infectious viral, bacterial,… »
Having to do with reducing inflammation. »
Substances that reduce or suppress inflammation. »
An immunoconjugate consisting of an anti-integrin monoclonal antibody covalently attached to the maytansinoid DM4, a derivative of the cytotoxic agent maytansine (DM1),… »
A humanized monoclonal antibody directed against the pro-inflammatory cytokine interleukin-6 (Il-6) with potential immunomodulating activity. Upon administration, anti-interleukin 6 monoclonal antibody ALD518… »
A human monoclonal antibody directed against the human inhibitory killer IgG-like receptor (KIR) with potential immunostimulating and antineoplastic activities. Anti-KIR monoclonal antibody… »
A fully humanized monoclonal antibody against killer-cell immunoglobulin-like receptors (KIR), with potential antineoplastic activity. Upon administration, anti-KIR monoclonal antibody IPH2102 binds to… »
A lipid nanoparticle formulation containing two small interfering RNAs (siRNAs) for kinesin spindle protein (KSP) and vascular endothelial growth factor (VEGF) with… »
A monoclonal antibody directed against the inhibitor receptor lymphocyte activation gene-3 (LAG-3), with potential immunomodulating and antineoplastic activities. Upon administration, the anti-LAG-3… »
An antibody-drug conjugate (ADC) composed of a humanized monoclonal antibody directed against the anti-solute carrier family 39 zinc transporter member 6 (SLC39A6;… »
A humanized monoclonal antibody against lysyl oxidase-like 2 (LOXL2), with potential antineoplastic activity. Anti-LOXL2 monoclonal antibody GS 6624 targets and specifically binds… »
A humanized monoclonal antibody directed against macrophage colony-stimulating factor (M-CSF) with potential anti-osteolytic activity. Anti-M-CSF monoclonal antibody MCS110 binds to M-CSF and… »
A human, recombinant monoclonal antibody (MoAb) against macrophage migration inhibitory factor (MIF), with potential immunomodulating, anti-inflammatory and antineoplastic activities. Upon intravenous administration,… »
Human tumor infiltrating lymphocytes (TIL) isolated from a melanoma patient and were engineered to react with the melanoma antigen MART-1 (Melanoma Antigen… »
A monoclonal antibody (MoAb) against extracellular melanin with tumor targeting activity. Anti-melanin monoclonal antibody PTI-6D2 binds to extracellular melanin, a melanocyte pigment… »
A fully human IgG1 monoclonal antibody directed against the cell surface glycoprotein mesothelin and conjugated to the maytansinoid DM4 with potential antineoplastic… »
Autologous chimeric immune receptor (CIR) T cells transfected with anti-mesothelin chimeric T cell receptor mRNA, with potential antineoplastic activity. The anti-mesothelin mRNA… »
A monoclonal antibody being studied in the treatment of some types of cancer. Monoclonal antibodies are made in the laboratory and can… »
A humanized monoclonal antibody against matrix metalloproteinase 9 (MMP-9), with potential antineoplastic activity. Upon administration, anti-MMP-9 monoclonal antibody GS-5745 binds to MMP-9… »
A monoclonal antibody recognizing human mucin, a cell surface antigen encoded by the MUC-1 gene. In normal tissue, mucin exists as heavily… »
Anti-Muellerian hormone type-2 receptor (573 aa, ~63 kDa) is encoded by the human AMHR2 gene. This protein plays a role in signaling,… »
A hormone made by the ovaries in females and the testicles in males. Anti-Mullerian hormone helps to form the male and female… »
An immunoconjugate consisting of a monoclonal antibody directed against a highly-expressed myeloma cell surface antigen covalently attached to the maytansinoid DM4, a… »
A monoclonal antibody against myostatin (MSTN) with potential anti-cachexia activity. Upon administration, anti-myostatin monoclonal antibody LY2495655 binds to and neutralizes the MSTN… »
An antibody drug conjugate (ADC) containing a fully human monoclonal antibody AGS-22 targeting the cell adhesion molecule nectin-4 and conjugated, via a… »
A human IgG1 monoclonal antibody directed against neuropilin-1 (NRP1), with potential antiangiogenic and antineoplastic activities. Upon intravenous administration, MNRP1685A specifically targets and… »
An autoimmune acute encephalitis caused by antibodies against the glutamate NMDA receptor. It usually affects females and in the majority of… »
A monoclonal antibody directed against the Notch receptor with potential antineoplastic activity. Anti-Notch receptor monoclonal antibody OMP-59R5 binds to Notch on the… »
A humanized monoclonal antibody directed against the Notch-1 receptor with potential antineoplastic activity. Upon administration, anti-Notch1 monoclonal antibody OMP-52M51 binds to Notch-1… »
A 26-base guanine-rich oligodeoxynucleotide aptamer with potential apoptotic induction activity. Upon administration, anti-nucleolin aptamer AS1411 targets and binds to nucleolin, a nucleolar… »
An agonistic monoclonal antibody against receptor OX40 (CD134), with potential immunostimulatory activity. Mimicking the natural OX4 ligand (OX40L), anti-OX40 monoclonal antibody selectively… »
Human autologous peripheral blood lymphocytes (PBLs) transduced with an anti-p53 T cell receptor gene with potential antineoplastic activity. PBLs are harvested from… »
An Fc-fusion protein containing a ligand of programmed death-1 (PD-1), with potential immunomodulating and antineoplastic activity. Anti-PD-1 fusion protein AMP-224 blocks the… »
A monoclonal antibody directed against the human programmed cell death 1 (PD-1) protein, with potential immunomodulating and antineoplastic activity. Although the exact… »
A fully human monoclonal antibody directed against the protein ligand PD-L1 (Programmed Death-1 Ligand 1) with immunomodulating and potential antineoplastic activities. Anti-PD-L1… »
A human, Fc optimized, monoclonal antibody directed against the protein ligand PD-L1 (programmed cell death-1 ligand 1) with potential immunomodulating and antineoplastic… »
A substance being studied in the treatment of glioblastoma (a type of brain tumor) that has come back. It binds to receptors… »
A humanized monoclonal antibody directed against the platelet-derived growth factor receptor (PDGFR) alpha with potential antineoplastic activity. Anti-PDGFR alpha monoclonal antibody MEDI-575… »
A humanized IgG1 monoclonal antibody directed against the placenta growth factor (PGF), with potential anti-angiogenic and antineoplastic activities. Anti-PGF monoclonal antibody RO5323441… »
A lipoplexed formulation consisting of short-interfering RNAs (siRNAs) directed against protein kinase N3 (PKN3) encapsulated in catiogenic and fusiogenic lipids with potential… »
A substance being studied in the treatment of glioblastoma (a type of brain tumor) that has come back. It binds to receptors… »
A humanized monoclonal antibody directed against placental growth factor (PLGF) with potential anti-angiogenic and antineoplastic acivities. Anti-PLGF monoclonal antibody TB-403 binds to… »
A neutralizing antibody against the prolactin receptor (PRLR) with potential antineoplastic activity. Upon administration, anti-prolactin receptor antibody LFA102 binds to PRLR and… »
An IgG1k fully human monoclonal antibody directed against the human prostate stem cell antigen (PSCA) with potential antineoplastic activity. Anti-PSCA fully human… »
A recombinant, human monoclonal antibody targeting an extracellular epitope of human prostate specific membrane antigen (PSMA) that is conjugated with a fluorescent… »
An antibody-drug conjugate (ADC) containing a fully human monoclonal antibody directed against prostate-specific membrane antigen (PSMA), conjugated via a stable, enzyme-cleavable linker… »
A recombinant T-cell engaging bispecific monoclonal antibody (BiTE) directed against human prostate specific membrane antigen (PSMA) and the CD3 epsilon subunit of… »
Used topically or systemically, natural or synthetic Anti-psoriatic agents relieve symptoms of psoriasis by controlling rapid growth of skin cells, reducing DNA… »
The determination of the amount of anti-Saccharomyces cerevisiae antibody present in a sample. »
A humanized IgG4 monoclonal antibody against the semaphorin 4D (SEMA4D; CD100) with potential immunomodulating and antineoplastic activities. Upon administration, anti-SEMA4D monoclonal antibody… »
The determination of the amount of anti-single stranded DNA IgG present in a sample. »
An antibody-drug conjugate (ADC) composed of a monoclonal antibody directed against SLIT and NTRK-like protein 6 (SLITRK6), covalently linked to the cytotoxic… »
A humanized monoclonal antibody recognizing the tumor-specific epitope of mucin-1 (TA-MUC1), with potential antineoplastic activity. Anti-TA-MUC1 monoclonal antibody PankoMab targets and binds… »
A recombinant human-mouse chimeric monoclonal antibody against human tissue factor (TF), with potential antiangiogenic, anticoagulant and anti-inflammatory activities. Upon administration, anti-TF monoclonal… »
An antibody-drug conjugate (ADC) comprised of a monoclonal antibody against human tissue factor (TF) covalently coupled, via a protease-cleavable peptide linker, to… »
A monoclonal antibody being studied in the treatment of kidney cancer, melanoma, and pulmonary fibrosis. Monoclonal antibodies are made in the laboratory… »
A monoclonal antibody directed against transforming growth factor-beta receptor type II (TGF-beta RII) with potential antineoplastic activity. Anti-TGF-beta RII monoclonal antibody IMC-TR1… »
A unit of anti-coagulation potency of antithrombin determined as the amount of antithrombin that neutralizes one unit of World Health Organization preparation… »
A purified gamma immunoglobulin (IgG) with immunosuppressive activity. Obtained from animals that have been immunized with human thymocytes, antithymocyte globulin (ATG) specifically… »
A humanized monoclonal antibody against human tissue factor (TF), with potential antiangiogenic, anticoagulant and anti-inflammatory activities. Upon administration, anti-TF monoclonal antibody MORAb-066… »
A substance being studied in the treatment of some types of cancer. It binds to a protein called TRAIL R1 on the… »
Sustancia en estudio para el tratamiento de ciertos tipos de cáncer. Se une a una proteína de la superficie de algunas células… »
A substance being studied in the treatment of some types of cancer. It binds to a protein called TRAIL-R2 on the surface… »
Sustancia en estudio para el tratamiento de algunos tipos de cáncer. Se une con una proteína que se llama TRAIL-R2 de la… »
An antibody drug conjugate containing the humanized monoclonal antibody, hRS7, against tumor-associated calcium signal transducer 2 (TACSTD2 or TROP2) and linked to… »
Drug treatment to reduce the activity of tumor necrosis factor, particulary to control inflammation in disease modalities. »
A humanized monoclonal antibody directed against the apoptotic ligand TNF-like weak inducer of apoptosis (TWEAK) with potential antineoplastic activity. Anti-TWEAK monoclonal antibody… »
Natural or synthetic Anti-ulcer Agents relieve and reduce the symptoms of ulcers in the stomach and upper small intestine, systemically and locally,… »
A pegylated, proprietary lipocalin that targets human vascular endothelial growth factor (VEGF), with potential antineoplastic activity. Pegylated anti-VEGF anticalin PRS-050 specifically targets… »
A monoclonal antibody directed against human Vascular Endothelial Growth Factor (VEGF), a protein that stimulates angiogenesis, and prevents VEGF from binding to… »
A fully human monoclonal antibody directed against the human vascular endothelial growth factor C (VEGFC or Flt4 ligand) with potential antiangiogenic… »
A monoclonal antibody being studied in the treatment of some types of cancer. Monoclonal antibodies are made in the laboratory and can… »
A substance being studied in the treatment of breast cancer that has come back. It binds to receptors for a protein called… »
Autologous human CD8-positive T-lymphocytes transduced with a recombinant retroviral vector encoding a chimeric T cell receptor (chimeric antigen receptor or CAR) consisting… »
A fully-human monoclonal antibody directed against human vascular endothelial growth factor receptor 3 (VEGFR-3; Flt-4) with antiangiogenic activity. Anti-VEGFR-3 monoclonal antibody IMC-3C5… »
A unit of unfractionated or low molecular weight heparin anticoagulation potency determined as the amount that neutralizes one unit of coagulation factor… »
A specific anticoagulation activity of unfractionated or low molecular weight heparin on factor Xa, expressed as a number of international anti-Xa heparin… »
A substance that keeps androgens (male hormones) from binding to proteins called androgen receptors, which can be found in prostate cells and… »
Treatment with drugs used to block production or interfere with the action of male sex hormones. »
Sustancia que impide que los andrógenos (hormonas masculinas) se unan a proteínas que se llaman receptores de andrógenos, los cuales se pueden… »
Prevention of the growth of new blood vessels. »
Prevención de la formación de nuevos vasos sanguíneos. »
A drug or substance that keeps new blood vessels from forming. In cancer treatment, antiangiogenesis agents may prevent the growth of new… »
A therapeutic regimen that uses synthetic compounds or natural substances to prevent the development of new blood vessels. »
Having to do with reducing the growth of new blood vessels. »
A proprietary, oral suspension containing a combination of agents comprised of a nonsteroidal anti-inflammatory agent, an alkylating agent, a histamine H2 antagonist… »
Relacionado con la reducción del crecimiento de nuevos vasos sanguíneos. »
A drug used to treat symptoms of anxiety, such as feelings of fear, dread, uneasiness, and muscle tightness, that may occur as… »
Something that prevents apoptosis. Apoptosis is a type of cell death in which a series of molecular steps in a cell leads… »
Something that prevents apoptosis. Apoptosis is a type of cell death in which a series of molecular steps in a cell leads… »
Algo que previene la apoptosis. La apoptosis es un tipo de muerte célular en la que una serie de etapas moleculares de… »
Agents used for the treatment or prevention of cardiac arrhythmias; they may effect the polarization-repolarization phase of the action potential, its excitability… »
A substance that kills bacteria or stops them from growing and causing disease. »
A family of substances capable of destroying or inhibiting the growth of bacteria. »
An Antibacterial Response is an induced humoral or cell-mediated reaction of the immune system to a bacterial antigen or infection. »
Sustancia que destruye las bacterias o les impide que crezcan y causen enfermedad. »
A drug used to treat infections caused by bacteria and other microorganisms. »
A method used to detect organisms that have resistance to a single concentration of antibiotics in an agar matrix. »
Administration of antibiotics with the intent of preventing bacterial infection. »
The mechanisms, functions, activities, or processes exhibited by microorganisms, especially bacteria, to resist or to become tolerant to antibiotics. »
An orally available, acid-stable diamine antibiotic, with potential antimicrobial activity against a variety of bacteria including Helicobacter pylori (H. pylori) and Mycobacterium… »
Treatment of bacterial infections with antibiotics. »
Medicamento usado para tratar las infecciones causadas por bacterias y otros microorganismos. »
Sustancia que combate muchos tipos de bacterias como la estreptomicina, la gentamicina y la neomicina. Un antibiótico aminoglucósido se usa para tratar… »
Tipo de medicamento contra el cáncer que impide el crecimiento celular al interferir con el ADN, el material genético de las… »
Tipo de medicamento contra el cáncer que impide el crecimiento celular al interferir con el ADN, el material genético de las… »
Tipo de medicamento contra el cáncer que impide el crecimiento celular al interferir con el ADN, el material genético de las… »
Los antibióticos son medicamentos potentes que combaten las infecciones bacterianas. Su uso correcto puede salvar vidas. Actúan matando las bacterias o impidiendo… »
Antibiotics are powerful medicines that fight bacterial infections. Used properly, antibiotics can save lives. They either kill bacteria or keep them from… »
A protein made by plasma cells (a type of white blood cell) in response to an antigen (a substance that causes the… »
The site at which an antibody makes direct physical contact with a corresponding epitope on an antigen. »
A plastic medium with a coating of monoclonal or polyclonal antibodies, often used to select or deplete a population of cells which… »
Antibody Degradation consists of conjugation, transport, oxidation, and/or proteolysis of members of a class of cell-surface or secreted B lymphocyte proteins that… »
The genetic or structural type for the constant region of an antibody. »
Treatment with an antibody, a substance that can directly kill specific tumor cells or stimulate the immune system to kill tumor… »
Concentration in serum of the antibody that recognizes a particular epitope expressed as the reciprocal of the highest serum dilution that produces… »
A unit of antibody concentration measured by comparison against a known concentration of antibodies in a standard reference specimen. »
A type of immune reaction in which a target cell or microbe is coated with antibodies and killed by certain types of… »
A type of immune reaction in which a target cell or microbe is coated with antibodies and killed by certain types of… »
A systemic therapy which ensures that a specific prodrug is not converted into the active moiety anywhere but at the sites where… »
A substance made up of a monoclonal antibody chemically linked to a drug. The monoclonal antibody binds to specific proteins or receptors… »
An antibody-drug conjugate (ADC) composed of a monoclonal antibody directed against a specific myeloma antigen and conjugated to monomethyl auristatin E (MMAE),… »
An antibody-drug conjugate (ADC) containing an antibody directed against the scr-like kinase Fyn3 (SC-16), conjugated to the cytotoxic agent D6.5, with potential… »
Treatment with injections of therapeutic substances linked with specific antibodies in order to directly destroy specific, usually cancerous, cells or to stimulate… »
The cytotoxicity of cells depending on antibody recognition. The killing of a target cell by a killer cell by means of… »
Cells of the lymphoid series that can react with antigen to produce specific cell products called antibodies. »
Treatment to manage or alleviate the fatigue and weight loss often associated with cancer. »
Describes a drug or effect that works against cachexia (loss of body weight and muscle mass). »
Drugs which reduce the fatigue and weight loss often associated with cancer. »
A small molecule with potential anticachexia activity. The anticachexia agent MT-102 may increase protein synthesis and decrease muscle protein breakdown. This may… »
A type of anticancer drug that blocks cell growth by interfering with DNA, the genetic material in cells. Also called antineoplastic antibiotic… »
Treatment to stop or prevent cancer. »
Describe un medicamento o un efecto contra la cachexia (pérdida de peso corporal y masa muscular). »
Having to do with preventing or delaying the development of cancer. »
Relacionado con la prevención o el retraso de la evolución del cáncer. »
An autoantibody that reacts with cardiolipin. Different immunoglobulin subclasses and isotypes are associated with different diseases and conditions. Some anticardiolipin antibodies prolong… »
An IgG autoantibody directed against cardiolipin. It is associated with thrombosis, spontaneous abortion, and complications during labor. »
An IgM autoantibody directed against cardiolipin. It is associated with hemolytic anemia. »
Any agent that binds to and blocks nicotinic and/or muscarinic receptors, thereby preventing the actions of the neurotransmitter acetylcholine (Ach) at these… »
Vomiting caused by expectation of discomfort or unpleasantness. »
A substance that is used to prevent and treat blood clots in blood vessels and the heart. Also called blood thinner. … »
Any agent capable of preventing blood clot formation. »
Sustancia que se usa para prevenir y tratar los coágulos de sangre en los vasos sanguíneos y el corazón. También se llama… »
Si tiene algún tipo de enfermedad del corazón o de los vasos sanguíneos o si tiene mala irrigación cerebral, su doctor puede… »
Drug treatment to thin the blood in order to prevent or reduce blood clot formation. »
A drug or other substance used to prevent or stop seizures or convulsions. Also called antiepileptic. »
Medicine to stop, prevent, or control seizures (convulsions). »
A form of drug hypersensitivity syndrome caused by anti-convulsants. »
Drug treatment to prevent, stop, or reduce the severity of seizures or convulsions, commonly used in cases of epilepsy or other seizure… »
Medicamento u otra sustancia que se usa para prevenir o interrumpir las crisis epilépticas o convulsiones. También se llama antiepiléptico. »
Proteína elaborada por las células plasmáticas (tipo de glóbulo blanco) en respuesta a un antígeno (sustancia que provoca que el cuerpo reaccione… »
Tipo de anticuerpo que se puede unir a dos antígenos diferentes al mismo tiempo. Los anticuerpos biespecíficos están en estudio para la… »
Anticuerpo contra el antígeno carcinoembriónico (ACE), una proteína presente en ciertos tipos de células cancerosas. »
Sustancia que producen ciertos glóbulos blancos como reacción al contacto con el virus de la inmunodeficiencia humana (VIH). »
Tipo de proteína producida en el laboratorio que se puede unir a sustancias del cuerpo, incluso a las células cancerosas. Hay muchas… »
Sustancia en estudio para el tratamiento de cáncer. Se elabora enlazando un anticuerpo monoclonal que se llama 170, que se une … »
Sustancia en estudio para el tratamiento de glioblastoma (un tipo de tumor cerebral) que volvió. Se une con los receptores de una… »
Sustancia en estudio para el tratamiento de glioblastoma (un tipo de tumor cerebral) que volvió. Se une con los receptores de una… »
Sustancia en estudio para el tratamiento de cáncer. Se une a una proteína que se llama factor de crecimiento de hepatocitos (FCH),… »
Anticuerpo monoclonal en estudio para el tratamiento de algunos tipos de cáncer. Los anticuerpos monoclonales se producen en el laboratorio y pueden… »
Anticuerpo monoclonal en estudio para el tratamiento de algunos tipos de cáncer. Los anticuerpos monoclonales se producen en el laboratorio y pueden… »
Sustancia en estudio para estudios de imaginología de algunos tipos de cáncer. M5A es un anticuerpo monoclonal que se une a una… »
Anticuerpo monoclonal en estudio para el tratamiento de algunos tipos de cáncer. Los anticuerpos monoclonales se producen en el laboratorio y pueden… »
Sustancia en estudio para el tratamiento de ciertos tipos de leucemia y linfoma. BC8 es un anticuerpo monoclonal que se une a… »
Anticuerpo que se puede unir a dos tipos diferentes de antígenos al mismo tiempo. Los anticuerpos monoclonales biespecíficos están en estudio para… »
Sustancia en estudio para el tratamiento de cáncer. Se une a una molécula que se llama GD2, que se encuentra en cantidades… »
Anticuerpo monoclonal en estudio para el tratamiento del cáncer de riñón, el melanoma y la fibrosis pulmonar. Los anticuerpos monoclonales se producen… »
Sustancia en estudio para el tratamiento de cáncer de hígado. HuAFP31 es un anticuerpo monoclonal que se puede unir a células tumorales… »
Tipo de anticuerpo producido en el laboratorio mediante la combinación de un anticuerpo humano con una pequeña porción de un anticuerpo monoclonal… »
Sustancia en estudio para el tratamiento de algunos tipos de cáncer. Se elabora al unir el anticuerpo monoclonal huC242 a una sustancia… »
Sustancia en estudio para el tratamiento de algunos tipos de cáncer y otras afecciones. El anticuerpo monoclonal humano MEDI-522 se une a… »
Sustancia en estudio para el tratamiento de los síndromes mielodisplásicos y algunos tipos de leucemia. Se una a la proteína CD33 en… »
Sustancia en estudio para el tratamiento de cáncer de páncreas en estadio avanzado. El anticuerpo monoclonal itrio 90 (Y 90) DOTA HuPAM4… »
Sustancia en estudio para el tratamiento de algunos tipos de cáncer. M5A es un anticuerpo monoclonal que se une a una proteína… »
Sustancia en estudio para el tratamiento de la ateroesclerosis (acumulación de grasa en las arterias). También está en estudio para… »
Anticuerpo monoclonal quimérico (compuesto de proteínas humanas y de ratón) que está en estudio para el tratamiento del cáncer de riñón avanzado… »
Sustancia en estudio para el tratamiento de cáncer de mama que volvió. Se une a los receptores de una proteína que se… »
Anticuerpo que se une a un virus e interfiere con su capacidad de infectar una célula. »
Medicamento que se usa para tratar la depresión. »
Medicamento usado para tratar la depresión. »
Los antidepresivos son medicinas que receta un médico para tratar la depresión. Estos medicamentos ayudan a mejorar la forma en que el… »
A drug used to treat depression. »
Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several monoamine oxidase inhibitors are useful as antidepressants apparently… »
The determination of the amount of antidepressant class drug present in a sample. »
Antidepressants are medicines that treat depression. Your doctor can prescribe them for you. They work to balance some of the natural chemicals… »
Sustancia que se usa para tratar la diarrea (evacuaciones intestinales frecuentes y acuosas). »
A substance used to treat diarrhea (frequent and watery bowel movements). »
Miscellaneous agents found useful in the symptomatic treatment of diarrhea. They have no effect on the agent(s) that cause diarrhea, but merely… »
Any of the synthetic analogues of vassopressin (ADH) with similar properties of the endogenous hormone, such as antidiuretic, increases arterial blood pressure… »
The determination of the amount of antidiuretic hormone present in a sample. »
A drug that prevents or reduces nausea and vomiting. »
Drugs used to prevent nausea or vomiting. Antiemetics act by a wide range of mechanisms. Some act on the medullary control centers… »
An Antiemetic Effect involves suppression of nausea and vomiting. Emesis is a complex process coordinated by a central emesis center located in… »
Medicamento que previene o reduce las náuseas y los vómitos. »
A drug or other substance used to prevent or stop seizures or convulsions. Also called anticonvulsant. »
Medicamento u otra sustancia que se usa para prevenir o interrumpir las crisis epilépticas o convulsiones. También se llama anticonvulsivo. »
A substance that keeps cells from making or using estrogen (a hormone that plays a role in female sex characteristics, the menstrual… »
Drug treatment to block the action of the female hormone estrogen. »
Sustancia que impide que las células elaboren o usen estrógeno (una hormona que juega un papel en la formación de las características… »
A type of drug that helps the blood clot. It prevents the breakdown of a protein called fibrin, which is the main… »
Natural or synthetic compounds usually administered orally, Antiflatulent Agents relieve or prevent flatulence, excess gas in the stomach and intestines, by adsorbing… »
A type of drug that stops cells from using folic acid to make DNA and may kill cancer cells. Certain antifolates are… »
Tipo de medicamento que impide que las células usen ácido fólico para elaborar ADN y podría destruir células cancerosas. Ciertos antifolatos se… »
A drug that treats infections caused by fungi. »
Substances that treat systemic or topical infections caused by fungi. Antifungal agents kill or inhibit the growth of fungi, by various… »
Drug treatment to destroy or inhibit the growth or multiplication of fungi. »
Medicamento que trata las infecciones causadas por hongos. »
Any substance that causes the body to make a specific immune response. »
Antigen Binding Interaction involves specific and high affinity non-covalent interaction (binding) of an endogenous antibody through intermolecular physical forces of attraction and… »
A key part of the immune system is the production of immunoglobulins (antibodies) by B cells to bind and inactivate specific foreign… »
A gene that encodes a product, termed an antigen, which stimulates the immune system and results in the production of antibodies. … »
Antigen KI-67 protein (3256 aa, ~359 kDa) is encoded by the human MKI67 gene. This protein is required for cell proliferation. … »
The event of providing fragments of foreign proteins, including viruses and bacteria, to the helper T cells. The presentation occurs through the… »
Antigen Presentation Interaction involves specific non-covalent interaction (binding) through intermolecular physical forces of attraction and spatial complementarity of T-Cell Antigen Receptors with… »
Invariant chain (Ii) associates with newly synthesized class II molecules in the endoplasmic reticulum (ER), an interaction that has been shown to… »
A cell that enables a T-lymphocyte to recognize an antigen by engulfing the antigen, breaking down the antigen into smaller fragments which… »
The process by which foreign molecules are taken up by antigen presenting cells, proteolytically cleaved, and displayed on the cell surface in… »
A cell that enables a T-lymphocyte to recognize an antigen by engulfing the antigen, breaking down the antigen into smaller fragments which… »
An in vitro test to assess the ability of peripheral blood mononuclear cells to proliferate in response to specific antigen stimulus. … »
A procedure to manufacture blood group antigens or cellular reagents for donor and recipient typing of blood or organs. »
Antigen Sensitization is a process of immunization with an antigen preparation that renders an immune-response involving generation of antibodies against the specific… »
Antigen Targeting involves specific and high affinity non-covalent interaction (binding) of an antibody reagent through intermolecular physical forces of attraction and spatial… »
In complement fixation tests, the smallest amount of antigen that will fix one unit of complement. »
A measure of an antigen potency defined as a number of antigen units per one milliliter of product. »
A type of immune cell that boosts immune responses by showing antigens on its surface to other cells of the immune… »
A vaccine made of antigens and antigen-presenting cells (APCs). APCs boost an immune response by presenting antigens on their surfaces to other… »
Antigen-presenting glycoprotein CD1d (335 aa, ~38 kDa) is encoded by the human CD1D gene. This protein is involved in lipid antigen… »
Cualquier sustancia que provoque en el cuerpo una respuesta inmunitaria específica. »
Sustancia que se puede encontrar en la sangre de las personas que sufren de cáncer de colon, otros tipos de cáncer o… »
Proteína que se encuentra en las células B (un tipo de glóbulo blanco). Se puede encontrar en cantidades mayores que las normales… »
Proteína que se encuentra en la superficie de algunas células de la médula ósea y de la sangre. »
Proteína que se encuentra en los melanocitos (células que elaboran el pigmento melanina) normales de la piel y la retina. También se… »
Sustancia que se puede encontrar en grandes cantidades en la sangre de pacientes con ciertos tipos de cáncer, incluso el cáncer de… »
Tipo de molécula que se encuentra en la superficie de la mayoría de las células del cuerpo. Los antígenos leucocitarios humanos tienen… »
Tipo de molécula que se encuentra en la superficie de la mayoría de las células del cuerpo. Los antígenos linfocitarios humanos tienen… »
Proteína que se encuentra en muchos tipos de tumores, pero no en la mayoría de los tejidos normales. Las vacunas que se… »
Proteína que se encuentra en los melanocitos (células que elaboran el pigmento melanina) normales de la piel y la retina. También se… »
Proteína que se encuentra en la superficie de algunos cánceres. »
Proteína elaborada por la próstata que se encuentra en la sangre. Las concentraciones de antígeno prostático específico en la sangre pueden ser… »
Compuesto de proteína y azúcar que se encuentra en la superficie de muchas células cancerosas, como las células de la mama, el… »
Proteína u otra molécula que pertenece únicamente a las células cancerosas o que es mucho más abundante en ellas. Por lo general,… »
A laboratory test to identify antibodies that can bind to the surface of red blood cells or platelets and destroy them. This… »
A group of islands in the Caribbean Sea, east of Saint Kitts and Nevis. »
The curved cartilage ridge on the flap of the ear that is parallel to the helix. »
Agents destructive to parasitic worms. They are used therapeutically in the treatment of helminthiasis in man and animal. »
The recombinant form of human antihemophilic factor (AH)) (Factor VIII) with coagulation promoting activity. Antihemophilic factor binds to factor IXa in the… »
Tipo de medicamento que bloquea la acción de las histaminas, las cuales pueden causar fiebre, picazón, estornudos, mucosidad nasal y lagrimeo. Las… »
A type of drug that blocks the action of histamines, which can cause fever, itching, sneezing, a runny nose, and watery… »
Treatment with drugs, surgery, or radiation in order to block the production or action of a hormone. Antihormone therapy may be used… »
Any substance used in the treatment of acute or chronic hypertension regardless of pharmacological mechanism. Antihypertensive agents include diuretics, alpha-adrenergic and beta-adrenergic… »
Natural or synthetic Antihypertensive Preparations reduce elevated blood pressure through diverse mechanisms: calcium channel (and conductance) blockage, beta- and alpha-adrenergic blockage, angiotensin-converting… »
Relacionado con reducir la inflamación. »
Any substance that treats, prevents, or inhibits the development of leukemia. »
Antileukoproteinase (132 aa, ~14 kDa) is encoded by the human SLPI gene. This protein is involved in the regulation of serine proteinase… »
An agent that reduces plasma lipids, such as cholesterol or low density lipoproteins (LDL), acting systemically or locally (intestines) to decrease fat… »
Serum from blood that contains antibodies that bind to human T cells. Antilymphocyte globulin is given to a patient before a stem… »
Immunoglobulins raised xenogeneically against lymphocyte populations. It is used both as a test for histocompatibility and in conjunction with other immunosuppressive… »
Agents used to treat malaria, and are usually classified based on action against plasmodia at different stages in their life cycle in… »
A drug that is very similar to natural chemicals in a normal biochemical reaction in cells but different enough to interfere with… »
Treatment of cancer that utilizes antimetabolite substances to disrupt DNA, RNA, or protein synthesis. »
Medicamento muy similar a las sustancias químicas naturales presentes en una reacción bioquímica normal en las células, pero lo suficientemente diferente como… »
An agent that prevents or impairs tumor metastasis. »
A substance that kills microorganisms such as bacteria or mold, or stops them from growing and causing disease. »
A method to determine the microbial susceptibility to two or more antibiotics. Numerical result translated into indifference, antagonism, synergism, or additive. … »
A microbial susceptibility test result in which the growth of microorganisms may be inhibited when higher than normal dosages of an antimicrobial… »
An Antimicrobial Effect involves interference with, or restraint of, the activities of biologic molecules and complexes, or cellular components involved in the… »
A microbial susceptibility test result in which the growth of microorganisms may be inhibited by the usually achievable concentrations of antimicrobial agent… »
A microbial susceptibility test result in which the growth of microorganisms is not inhibited by the usually achievable concentrations of antimicrobial agent… »
A microbial susceptibility test result in which the growth of microorganisms is not inhibited by the usually achievable concentrations of antimicrobial agent… »
A microbial susceptibility test result in which the growth of microorganisms is inhibited by the usually achievable concentrations of antimicrobial agent when… »
Sustancia que destruye microorganismos, tales como las bacterias o el moho, o les impide crecer y causar enfermedad. »
A type of drug that blocks cell growth by stopping mitosis (cell division). Antimicrotubule agents interfere with microtubules (cellular structures that help… »
Tipo de medicamento que bloquea el crecimiento celular al impedir la mitosis (división celular). Los antimicrotúbulos interfieren con los microtúbulos (estructuras celulares… »
The determination of the amount of antimitochondrial antibodies present in a sample. »
A type of drug that blocks cell growth by stopping mitosis (cell division). They are used to treat cancer. Also called mitotic… »
Tipo de medicamento que bloquea el crecimiento celular al impedir la mitosis (división celular). Los antimitóticos se usan para tratar el… »
A non-nucleoside reverse transcriptase inhibitor. Antimoniotungstate is a mineral condensed ion with a cryptic structure. »
An element with atomic symbol Sb, atomic number 51, and atomic weight 121.76. »
Natural or synthetic Antimuscarinic Agents inhibit acetylcholine neurotransmitter action at muscarinic receptors. Antimuscarinic drugs are used as antiarrhythmic, antiparkinson, antiasthmatic, and antispasmodic… »
Que impide la formación de neoplasias (crecimientos que se pueden volver cancerosos). »
Blocking the formation of neoplasms (growths that may become cancer). »
A substance that inhibits the maturation, growth or spread of tumor cells. »
An antineoplastic agent that replaces hydrogen atom(s) in nucleophilic moieties with alky radical(s), hindering proper function. Alkylating agents exhibit cytotoxic effects through… »
A type of anticancer drug that blocks cell growth by interfering with DNA, the genetic material in cells. Also called anticancer antibiotic… »
Plant-derived compound used to treat cancer. »
A type of vaccine that is usually made from a patient's own tumor cells or from substances taken from tumor cells. A… »
A substance isolated from normal human blood and urine that is being tested as a type of treatment for some tumors and… »
Sustancia aislada de la sangre y orina normal de un humano, que se encuentra bajo prueba como un tipo de tratamiento para… »
A piperidinedione antineoplaston with potential antineoplastic activity. Antineoplaston A10 was originally isolated from human urine but is now synthetically derived. … »
A peptide, amino acid derivative, and/or organic acid extracted from blood serum, urine, or synthesized chemically, that inhibits the methylation of nucleic… »
A 4:1 mixture of phenylacetate and phenylacetylgluatmine, degradation products of the antineoplaston agent A10. Antineoplaston AS2-1 inhibits the incorporation of L-glutamine… »
A complimentary/alternative cancer therapy that uses antineoplastons to protect the body from disease. »
An autoimmune antibody that is directed against structures within the nucleus of the cell. »
The determination of the amount of antinuclear antibodies present in a sample. »
Par de genes (unidades de herencia que pasan de padres a hijos) que hacen que la célula elabore una proteína que controla… »
A type of gene that makes a protein called a tumor suppressor protein that helps control cell growth. Mutations (changes in DNA)… »
A substance that protects cells from the damage caused by free radicals (unstable molecules made by the process of oxidation during normal… »
Sustancia que protege las células de los daños que causan los radicales libres (moléculas inestables elaboradas por el proceso de oxidación durante… »
Los antioxidantes son sustancias que pueden proteger sus células de los efectos de los radicales libres. Los radicales libres son moléculas producidas… »
Antioxidants are man-made or natural substances that may prevent or delay some types of cell damage. Antioxidants are found in many foods,… »
Treatment with antioxidants in order to protect cells against damage caused by oxygen-free radicals. »
A drug used to treat infections caused by bacteria and parasites. It is also used in the treatment of some cancers. … »
Any agent that is effective against infections caused by parasitic organisms and is able to inhibit their growth or kill them. This… »
Medicamento que se usa para el tratamiento de infecciones ocasionadas por bacterias o parásitos. También se usa para el tratamiento del algunos… »
Any agent that is used in the treatment of Parkinson's disease. Antiparkinsonian agents act by restoring the striatal balance between dopaminergic and… »
A cream formulation containing aluminum chlorohydrate with astringent and antiperspirant activities. Upon topical application of F511 cream, aluminium chlorohydrate forms a gel… »
The determination of the amount of antiphospholipid antibodies present in a sample. »
A syndrome associated with a variety of diseases, notably systemic lupus erythematosus and other connective tissue diseases, thrombopenia, and arterial or venous… »
An agent that inhibits platelet aggregation and reduces coagulation in the circulatory system. »
Drug treatment to block the action of the female hormone progesterone. »
A substance that prevents cells from making or using progesterone (a hormone that plays a role in the menstrual cycle and… »
Sustancia que impide que las células elaboren o usen progesterona (hormona que participa en el ciclo menstrual y el embarazo). Las antiprogestinas… »
Drug treatment to block the action of the female hormone prolactin. »
Substances that are destructive to protozoans. »
An Antipruritic Effect involves suppression of an itching sensation caused by histamine stimulation of epidermal nerve endings. Inhibition of histamine or histamine… »
Tipo de medicamento que se emplea para tratar los síntomas de la psicosis, tales como las alucinaciones (visiones, sonidos, olores, gustos… »
A type of drug used to treat symptoms of psychosis. These include hallucinations (sights, sounds, smells, tastes, or touches that a… »
A type of drug used to treat symptoms of psychosis. These include hallucinations (sights, sounds, smells, tastes, or touches that a… »
The determination of the amount of any antipsychotic drug present in a sample. »
A relation in which no element is in relation to itself. »
Treatment with drugs that inhibit the ability of the human immunodeficiency virus (HIV) or other types of retroviruses to multiply in the… »
Used systemically or topically, natural or synthetic Antirheumatic Preparations relieve and control the symptoms of rheumatic diseases (rheumatoid arthritis) by reducing inflammation… »
Substances that control the excessive secretion of sebum, the oily secretions from sweat glands. »
Small pieces of DNA or RNA that can bind to specific molecules of RNA. This blocks the ability of the RNA to… »
A substance that has been studied in the treatment of cancer and is being studied in the treatment of rheumatoid arthritis and… »
Small pieces of DNA that can bind to specific molecules of RNA and block the cell’s ability to use the RNA to… »
Small pieces of DNA or RNA that can bind to specific molecules of RNA. This blocks the ability of the RNA to… »
Treatment with antisense oligonucleotides. These are small pieces of DNA or RNA that can bind to specific molecules of RNA. This… »
Antisense Oligonucleotides, short synthetic segments of DNA or RNA, designed with a sequence complimentary to a specific mRNA that target and bind… »
Having a DNA sequence complementary to that of a messenger RNA molecule; the non-coding strand in double-stranded DNA. »
Small pieces of RNA that can bind to specific molecules of RNA and block the cell’s ability to use the RNA to… »
The use of nucleic acid oligomers to bind to a specific mRNA to deter protein production. »
Treatment with antisense oligonucleotides. These are small pieces of DNA or RNA that can bind to specific molecules of RNA. This… »
A blood serum or immunoglobulin fraction that contains antibodies against specific antigens obtained from previously immunized animals. »
Describes behavior that ignores the rights of others and the practices and laws of society. »
Describe la conducta que ignora los derechos de los otros, y las prácticas y leyes de la sociedad. »
Describes behavior that ignores the rights of others and the practices and laws of society. »
A disorder characterized by a pervasive pattern of disregard for and violation of the rights of others that is manifested in childhood… »
Any agent that prevents or relieves muscle spasms, mainly ones originating from smooth muscle contractions of the stomach, bladder and intestines. … »
A binary relation such that if a is related to b and b is related to a, then a equals b. … »
Delivery of electrical impulses to the heart at a faster rate than the intrinsic rate during an episode of tachycardia, in an… »
The determination of the amount of antithrombin activity in a sample. »
A recombinant form of human antithrombin with anticoagulant activity. Antithrombin alfa blocks thrombin activity and thus thrombus formation. It is used in… »
The determination of the amount of antithrombin antigen present in a sample. »
A rare disorder characterized by the presence of low levels of antithrombin III which prohibits the formation of blood clots. It may… »
Antithrombin-III (464 aa, ~53 kDa) is encoded by the human SERPINC1 gene. This protein is involved in the negative regulation of serine… »
Serum from blood that contains antibodies that bind to human T cells. Antithymocyte globulin is given to a patient before a stem… »
Agents that are used to treat hyperthyroidism by reducing the excessive production of thyroid hormones. »
A projection or prominence opposite the tragus that is found on the lower exterior portion of the ear. »
A binary relation such that an element a is related to an element b, and b is in turn related to an… »
Any agent that is active against Mycobacterium tuberculosis and can be used in the treatment of or in the prevention of… »
Describes a drug or effect that works against tuberculosis (a contagious bacterial infection that usually affects the lungs). »
Describe un medicamento o efecto que trabaja contra la tuberculosis (infección bacterial contagiosa que por lo general afecta los pulmones). »
Having to do with stopping abnormal cell growth. »
A type of anticancer drug that blocks cell growth by interfering with DNA, the genetic material in cells. Also called anticancer antibiotic… »
Methods of investigating the effectiveness of anticancer cytotoxic drugs and biologic inhibitors. These include in vitro cell-kill models and cytostatic dye exclusion… »
An antitumor response involves destruction of cancer tumor cells primarily by activated T-cells induced to react to antigens recognized as foreign and… »
Relacionado con lo que impide el crecimiento anormal de las células. »
Any substance that is capable of relieving or suppressing coughing. »
A drug used to treat infections caused by viruses. »
Any agent that can treat or prevent viral infections by interfering with the viral replication cycle. »
An Antiviral Response is an induced humoral or cell-mediated reaction of the immune system to a viral antigen or infection. »
Treatment of viral infections with agents that prevent viral replication in infected cells without impairing the host cell function. »
Medicamento que se usa para el tratamiento de infecciones ocasionadas por un virus. »
Medicamento contra el cáncer que es un tipo de antibiótico contra el cáncer. »
Tipo de antibiótico que proviene de ciertos tipos de la bacteria Streptomyces. Las antraciclinas se usan en el tratamiento de muchos tipos… »
The number of small ovarian follicles (approximately 2-8 mm in diameter) that can be detected and counted with transvaginal ultrasonography, to determine… »
Tipo de medicamento contra el cáncer. »
El ántrax es una enfermedad causada por el Bacillus anthracis, un microbio que vive en la tierra. Muchas personas han oído hablar… »
A dietary supplement containing extract from the medicinal fungus Antrodia cinnamomea with potential antiangiogenic, hepatoprotective and antioxidant activities. The components in Antrodia… »
A chamber formation in an organ. »
The initial part of the pyloric canal of the stomach. This site contains endocrine cells that produce gastrin and somatostatin. »
Sustancia que se une a una molécula que se llama antígeno Lewis Y que se encuentra en muchos tipos de células tumorales… »
This gene plays a role in cell-matrix adhesion. »
Human ANTXR1 wild-type allele is located in the vicinity of 2p13.1 and is approximately 236 kb in length. This allele, which encodes… »
The opening of the rectum to the outside of the body. »
This gene is involved in skeletal system development. »
Human ANXA2 wild-type allele is located in the vicinity of 15q22.2 and is approximately 56 kb in length. This allele, which encodes… »
This gene is involved in anticoagulation processes and mediates lipid binding. »
Human ANXA5 wild-type allele is located within 4q27 and is approximately 29 kb in length. This allele, which encodes annexin A5 protein,… »
This gene plays a role in lipid binding regulation and the overexpression of the gene has been isolated in acute myelocytic… »
Human ANXA8 wild-type allele is located in the vicinity of 10q11.2 and is approximately 24 kb in length. This allele, which encodes… »
Feelings of fear, dread, and uneasiness that may occur as a reaction to stress. A person with anxiety may sweat, feel restless… »
A category of psychiatric disorders which are characterized by anxious feelings or fear often accompanied by physical symptoms associated with anxiety. … »
An anxiety disorder in which the symptoms of anxiety have been determined to be the direct physiological consequence of a general medical… »
A level of sedation in which a person is very relaxed and may be awake. The person is able to answer questions… »
A drug used to treat symptoms of anxiety, such as feelings of fear, dread, uneasiness, and muscle tightness, that may occur as… »
A drug used to treat symptoms of anxiety, such as feelings of fear, dread, uneasiness, and muscle tightness, that may occur as… »
Medicamento que se usa para tratar los síntomas de ansiedad, como los sentimientos de temor, terror, incomodidad y tensión muscular, que se… »
One, some, every, or all without specification. »
A data type comprised of the basic properties of a data value. »
No specification on the details of the primary tumor growth. »
A drug used to prevent nausea and vomiting caused by chemotherapy. It is also used to prevent nausea and vomiting after… »
Medicamento que se usa para prevenir las náuseas y los vómitos producidos por la quimioterapia. También se usa para prevenir las náuseas… »
The largest artery in the body. It carries oxygen-rich blood away from the heart to vessels that reach the rest of the… »
Es la arteria más grande del cuerpo. Se encarga del transporte de sangre oxigenada del corazón hacia los vasos sanguíneos distribuidos por… »
Pathology involving the thoracic, thoracoabdominal, or abdominal aorta (including aneurysms). »
The layer of cells that lines the lumen of the aorta. »
The smooth muscle tissue present in the tunica media which is the middle layer of the aortic wall. »
The connection where the graft joins the aorta usually less than or equal to 3 mm from insertion point. »
A sac formation resulting from the localized dilatation of the wall of the aorta. »
A malignant vascular neoplasm arising from the aorta. »
The curved section of the aorta between the ascending and the descending tracts. The brachiocephalic, left common carotid and left subclavian arteries… »
An artery originating from the aortic arch. »
A syndrome resulting from structural defects of the arteries that arise from the aortic arch. Signs and symptoms include weakness, dizziness, arm… »
Dilation of the valve between the left ventricle of the heart and the aorta by inflating a balloon. »
A small mass that is located in the inferior surface of the aortic arch. It functions as a peripheral chemoreceptor and is… »
Congenital narrowing of a segment of the aorta. Signs and symptoms include hypertension, muscle weakness, shortness of breath, headaches and leg… »
A progressive tear in the aorta characterized by a separation of the media layer from the outer-most layer. »
Damage to the aorta from traumatic or pathologic processes. »
The opening in the diaphragm that allows for passage of the descending aorta. »
Any portion of the aorta including the ascending and descending aorta, and aortic arch or a portion of the aortic orifice of… »
Narrowing of the orifice of the aortic valve or of the supravalvular or subvalvular regions. »
A valve that is located between and controls the flow of blood from the left ventricle of the heart and the… »
A rare congenital heart defect characterized by the complete failure of the aortic valve to open. It is manifested during infancy with… »
A heart disorder characterized by a defect in aortic valve structure or function. »
Dysfunction of the aortic valve characterized by incomplete valve closure. »
The backward flow of blood from the aorta into the left ventricle, owing to insufficiency of the aortic semilunar valve; it may… »
Surgery performed with the purpose of replacing a degenerated, calcified, malformed, dysfunctional, etc. aortic valve with a bioprosthetic, homograft, or autograft… »
A benign or malignant extra-adrenal parasympathetic paraganglioma that arises from paraganglia adjacent to the base of the heart and great vessels. … »
Inflammation of the aorta. Causes include trauma, infectious disorders, and connective tissue disorders. »
Surgery in which a healthy blood vessel taken from another part of the body is used to make a new path for… »
A dimeric complex of related bZIP JUN, FOS, MAF and ATF transcription factors that must dimerize in order to bind to AP1… »
Activator Protein 2. Originally identified as a cellular transcription factor that binds the enhancer region of SV40. It is encoded… »
A substance being studied in the treatment of soft tissue and bone cancers. It is also being studied in the treatment of… »
Sustancia en estudio para el tratamiento de los cánceres del tejido blando y del hueso. También está en estudio para el tratamiento… »
A substance being studied in the treatment of head and neck cancer. It may kill cancer cells by carrying an anticancer drug… »
Sustancia en estudio para el tratamiento del cáncer de cabeza y cuello. Podría destruir las células cancerosas al dirigir el medicamento contra… »
Nutriente del complejo de la vitamina B que el cuerpo necesita en pequeñas cantidades para funcionar y mantenerse sano. Las bacterias que… »
This gene is involved in pro-apoptotic regulation through caspase interaction. »
Human APAF1 wild-type allele is located in the vicinity of 9q22.32 and is approximately 90 kb in length. This allele, which encodes… »
A naphthydridine derivative of the broad spectrum, semisynthetic ampicillin with antibacterial activity. Apalcillin specifically binds to and inactivates penicillin-binding proteins (PBPs) located… »
The sodium salt of a naphthydridine derivative of the broad spectrum, semisynthetic ampicillin with antibacterial activity. Apalcillin specifically binds to and inactivates… »
Órganos que toman los alimentos y los convierten en productos que el cuerpo puede usar para estar sano. Los desperdicios que el… »
Órganos sexuales responsables de la reproducción humana. En las mujeres, este sistema incluye los ovarios, las trompas de Falopio, el útero,… »
Conjunto de órganos que participan en la respiración; incluye la nariz, la garganta, la laringe, la tráquea, los bronquios y los… »
Los aparatos para movilidad asistida lo ayudan a caminar o a moverse de un lugar a otro si está discapacitado o tiene… »
A room or suite of rooms designed as a residence and generally located in a building occupied by more than one household… »
An orally bioavailable, small-molecule receptor tyrosine kinase inhibitor with potential antiangiogenic and antineoplastic activities. Apatinib selectively binds to and inhibits vascular endothelial… »
An indolequinone bioreductive prodrug and analog of mitomycin C with potential antineoplastic and radiosensitization activities. Apaziquone is converted to active metabolites in… »
This gene is involved in synaptic vesicle exocytosis. »
Human APBA1 wild-type allele is located within 9q13-q21.1 and is approximately 245 kb in length. This allele, which encodes amyloid beta A4… »
This gene plays a role in neuronal transport. »
Human APBA2 wild-type allele is located within 15q11-q12 and is approximately 281 kb in length. This allele, which encodes amyloid beta A4… »
This gene is involved in the modulation of amyloid beta A4 precursor protein proteolysis. »
Human APBA3 wild-type allele is located in the vicinity of 19p13.3 and is approximately 11 kb in length. This allele, which encodes… »
A type of immune cell that boosts immune responses by showing antigens on its surface to other cells of the immune… »
This gene plays a role in signal transduction. It is involved in both adhesion and migration of cells. »
A vaccine made of antigens and antigen-presenting cells (APCs). APCs boost an immune response by presenting antigens on their surfaces to other… »
Human APC wild-type allele is located within 5q21-q22 and is approximately 108 kb in length. This allele, which encodes adenomatosis polyposis coli… »
This gene is involved in signal transduction and cell cycle regulation. »
Human APC2 wild-type allele is located in the vicinity of 19p13.3 and is approximately 23 kb in length. This allele, which encodes… »
A drug used to treat prostate cancer that has spread. It is made from immune system cells collected from a patient with… »
Medicamento que se usa para tratar el cáncer de próstata que se ha diseminado. Se elabora con células del sistema inmunitario de… »
A vaccine made from immune system cells taken from a patient with prostate cancer and frozen for future use. The cells are… »
Vacuna elaborada a partir de células del sistema inmunitario de un paciente de cáncer de próstata y congeladas para usar en el… »
Proteína elaborada por la próstata que se encuentra en la sangre. Las concentraciones de APE en la sangre pueden ser más altas… »
Cantidad de la proteína antígeno prostático específico (APE) en la sangre que no está adherida a otras proteínas. … »
A regimen consisting of cytarabine, cisplatin and etoposide, used for the treatment of recurrent and refractory, childhood Hodgkin's lymphoma. »
Cantidad total de antígeno prostático específico (APE) en la sangre. Incluye la cantidad de APE libre y la cantidad de APE adherido… »
A regimen consisting of dactionmycin, cisplatin and etoposide, used for the treatment of poor-prognosis metastatic gestational trophoblastic tumors. »
This gene plays a role in the degradation of oxidatively-damaged proteins in living cells. »
Human APEH wild-type allele is located in the vicinity of 3p21.31 and is approximately 95 kb in length. This allele, which encodes… »
Apelin (77 aa, ~9 kDa) is encoded by the human APLN gene. This protein is involved in both the inhibition of HIV-1… »
Bolsa pequeña, parecida a un dedo que sobresale del ciego (la primera parte del intestino grueso, cerca del final del intestino… »
Cirugía para extirpar el apéndice (bolsa en forma de dedo al final de la primera parte del intestino grueso). »
El apéndice es un órgano pequeño, en forma de tubo, unido a la primera parte del intestino grueso. Está ubicada en la… »
Deseo de satisfacer una necesidad física o mental, por ejemplo con comida, relaciones sexuales o aventura. »
The lowest superficial part of the heart which is situated behind the left 5th intercostal space. »
The rounded, uppermost part of the lung, located above the level of the sternal end of the first rib. »
The part of the pericardial sac that surrounds the great vessels. »
The lowest part of the prostate gland adjacent to the superior fascia of the urogenital diaphragm. »
The anterior extreme of the tongue which can be made pointed for sensing or probing and which rests against the lingual aspect… »
This gene is involved in DNA repair processes. »
Human APEX1 wild -type allele is located within 14q11.2-q12 and is approximately 13 kb in length. This allele, which encodes DNA-(apurinic or… »
This gene plays a role in DNA recognition and repair. »
Human APEX2 wild-type allele is located in the vicinity of Xp11.21 and is approximately 7 kb in length. This allele, which encodes… »
A controlled-release formulation of a biodegradable poly(ortho ester) polymer, encapsulating the indazole derivative granisetron, with antiemetic activity. Upon administration of APF530, the… »
The numerical sum between zero and ten that is computed from individual values of zero to two that are assigned to five… »
The numerical sum between zero and ten that is computed from individual values of zero to two that are assigned to five… »
The numerical sum between zero and ten that is computed from individual values of zero to two that are assigned to five… »
The numerical sum between zero and ten that is computed from individual values of zero to two that are assigned to five… »
The numerical sum between zero and ten that is computed from individual values of zero to two that are assigned to five… »
The numerical sum between zero and ten that is computed from individual values of zero to two that are assigned to five… »
A test devised by Dr. Virginia Apgar to assess the overall health of a newborn upon birth. The test is administered at… »
Absence of crystalline lens totally or partially from field of vision, from any cause except after cataract extraction. Aphakia is mainly congenital… »
Aphasia is a disorder caused by damage to the parts of the brain that control language. It can make it hard for… »
The point in the earth's orbit furthest away from the sun. »
A procedure in which blood is collected, part of the blood such as platelets or white blood cells is taken out, and… »
A tetracyclic diterpene antibiotic isolated from the fungus Cephalosporium aphidicola and other fungal species with potential antineoplastic activity. Aphidicoline glycinate blocks… »
A term referring to the inability to speak. It may result from injuries to the vocal cords or may be functional… »
A genus of non-enveloped, spherical viruses with T=pseudo3 icosahedral capsid, in the family Picornaviridae. The genome is composed of a linear, single-strand… »
The act of producing active pharmaceutical ingredients from raw materials. »