| Health / Medical Topics |
APOB wt Allele
Human APOB wild-type allele is located within 2p24-p23 and is approximately 43 kb in length. This allele, which encodes apolipoprotein B-100 protein, is involved in both transport and cellular binding of lipoprotein particles. Mutation of the gene is associated with both familial ligand-defective apolipoprotein B-100 and familial hypobetalipoproteinemia type 1. (NCI Thesaurus)
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