| Health / Medical Topics |
Arginine Vasopressin Receptor 2
Arginine Vasopressin Receptor 2 is also known as the V2 receptor. The V2 receptor is expressed in the kidney tubule, predominantly in the distal convoluted tubule and collecting ducts, where its primary property is to respond to the pituitary hormone arginine vasopressin (AVP) by stimulating mechanisms that concentrate the urine and maintain water homeostasis in the organism. When the function of this gene is lost, the disease Nephrogenic Diabetes Insipidus (NDI) results. AVPR2 expression has also been described in fetal lung tissue and lung cancer associated with alternative splicing. (NCI Thesaurus/LocusLink)
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