Axitinib

Pronunciation

Definition 1

A drug used to treat advanced renal cell carcinoma (the most common type of kidney cancer). It is used in patients who have not gotten better with other anticancer drugs. It is also being studied in the treatment of other types of cancer. Axitinib blocks the action of proteins called growth factor receptors and may prevent the growth of new blood vessels that tumors need to grow. It is a type of tyrosine kinase inhibitor and a type of antiangiogenesis agent. Also called Inlyta. (NCI Dictionary)

Definition 2

An orally bioavailable tyrosine kinase inhibitor. Axitinib inhibits the proangiogenic cytokines vascular endothelial growth factor (VEGF) and platelet-derived growth factor receptor (PDGF), thereby exerting an anti-angiogenic effect. (NCI Thesaurus)

Definition 3

A substance that is being studied in the treatment of cancer. It belongs to the families of drugs called angiogenesis inhibitors and protein tyrosine kinase inhibitors. (NCI Dictionary)

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