Health / Medical Topics

    BDNF wt Allele

    Human BDNF wild-type allele is located in the vicinity of 11p14.1 and is approximately 67 kb in length. This allele, which encodes brain-derived neurotrophic factor protein, is involved in both stress response regulation and in the survival of striatal neurons. Expression of the allele is decreased in both Alzheimer's and Huntington disease. (NCI Thesaurus)




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