Caspase-Independent Apoptosis

Any apoptotic process that involves pathways that activate intracellular proteolytic caspases.

Caspase-9 (416 aa, ~46 kDa) is encoded by the human CASP9 gene. This protein is involved in proteolysis and caspase-dependent apoptosis. …

Caspase-8 (479 aa, ~55 kDa) is encoded by the human CASP8 gene. This protein plays a role in proteolysis, angiogenesis and caspase-induction…

Caspase-7 (303 aa, ~34 kDa) is encoded by the human CASP7 gene. This protein is involved in caspase-mediated apoptosis and proteolysis. …

Caspase-6 (293 aa, ~33 kDa) is encoded by the human CASP6 gene. This protein plays a role in caspase activation and…

Caspase-5 (434 aa, ~50 kDa) is encoded by the human CASP5 gene. This protein is involved in both apoptosis and proteolysis. …