| Health / Medical Topics |
CBLB wt Allele
Human CBLB wild-type allele is located in the vicinity of 3q13.11 and is approximately 211 kb in length. This allele, which encodes E3 ubiquitin-protein ligase CBL-B protein, plays a role in protein degradation and the negative regulation of tyrosine kinase signaling pathways in the immune system. (NCI Thesaurus)
YOU MAY ALSO LIKE
This gene plays a role in the regulation of T cell activation.
Human CBL wild-type allele is located in the vicinity of 11q23.3 and is approximately 102 kb in length. This allele, which encodes…
The cellular homologue of v-cbl, CBL protein is expressed in a range of hemopoietic lineages. Malignancies are associated with translocations of…
This gene plays a role in signal transduction and the regulation of protein degradation.
A fusion protein encoded by the CBFB/MYH11 fusion gene. This protein is comprised of most of the core-binding factor subunit beta fused…
A fusion gene that results from a chromosomal inversion inv(16)(p13q22) which fuses the 5' portion of the CBFB gene with the 3'…
