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Chronic Kidney Disease
Definition 1
Gradual and usually permanent loss of kidney function resulting in renal failure. Causes include diabetes, hypertension, and glomerulonephritis. (NCI Thesaurus)
Definition 2
A disorder characterized by gradual and usually permanent loss of kidney function resulting in renal failure. (NCI Thesaurus/CTCAE)
Definition 3
Chronic kidney disease is defined as either kidney damage or GFR less than 60 ml/min/1.73 m2 for greater than or equal to 3 months. Kidney damage is de?ned as pathologic abnormalities or markers of damage, including abnormalities in blood or urine tests or imaging studies. (NCI Thesaurus/CDISC)
More information
You have two kidneys, each about the size of your fist. Their main job is to filter wastes and excess water out of your blood to make urine. They also keep the body's chemical balance, help control blood pressure, and make hormones.
Chronic kidney disease (CKD) means that your kidneys are damaged and can't filter blood as they should. This damage can cause wastes to build up in your body. It can also cause other problems that can harm your health. Diabetes and high blood pressure are the most common causes of CKD.
Treatment may include medicines to lower blood pressure, control blood glucose, and lower blood cholesterol. CKD can get worse over time. CKD may lead to kidney failure. The only treatment options for kidney failure are dialysis or a kidney transplantation.
You can take steps to keep your kidneys healthier longer:
• Choose foods with less salt (sodium)
• Keep your blood pressure below 130/80
• Keep your blood glucose in the target range, if you have diabetes (NIH: National Institute of Diabetes and Digestive and Kidney Diseases)
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